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287 HOSSAIN,         S.;   SALAM,       M.A.;        day after surgery with a plane film and
             KHAN, S.A. & HOSSAIN, A.Z.M.Z. (Dept.                found 100% stone clearance.
             of Urology, Dhaka Medical College, Dhaka). USE
             OF HOLMIUM: YAG LASER LITHOTRIPSY                    Ureteroscopy and Lithotripsy using the
             FOR TREATMENT OF URETERAL  STONES.                   Holmium: YAG Laser is effective and safe
             Bang.Med. J.,  2006, 35 (2), 61-62.                  in terms of rapid fragmentation and
                                                                  clearance for the treatment of ureteric stone.
             For stone fragmentation a variety of                 Chance of stone migration is negligible.
             lithotripter can be used. Though widely used,
             urologists are facing various complications          288  JAHAN, S.; HOSSAIN, M.M. (Dept.
             with pneumatic lithotripsy e.g. ureteal injury,      of Pediatrics Nephrology, Bangabandu
             bleeding and ureteral perforations during the        Sheikh Mujib Medical University, Shahbag,
             procedure.                                           Dhaka) & ISLAM, M.S.  (Dept. of Urology,
                                                                  Bangabandhu      Sheikh     Mujib     Medical
             Since 1990 the Holmilum: YAG Laser has               University, Shahbag,  Dhaka).  Spot urinary
             been used in urology for stone fragmentation         protein/osmolality ratio as a  predictor  for
             with better outcome because thermal effect is        proteinuria of nephrotic range. Bang. Med. Res.
             limited to a few millimeters with a penetration      Counc. Bul.,  2007, 33 (2) 65-68.
             depth of only 0.5 mm. The purpose of this
             study is to evaluate the lithotripsy quality the     A prospective study was carried out on  50
             use Holmium: YAG Laser and its outcome for           patients  (age  1-15 years) with nephrotic range
             the treatment of ureteral stone.                     of proteinuria to determine the  correlation  of
                                                                  24-hour  urinary total protein with spot urinary
                                                                                                         urinary
                                                                                                 and
                                                                                         ratio
                                                                  protein
                                                                            /creatinine
             The researchers treated 30 patients, male 24         protein/osmolality ratio. Another 50  patients
             and female 6, age 20 to 50 years, between            having no proteinuria grouped as control.
             March 2004 to January 2006 using the                 Twenty-four  hours urine and spot urine were
             Holmium: YAG laser under spinal anaesthesia.         collected from each child and were analyzed for
             All cases were purposively selected from OPD         total volume,  total protein, creatinine  and
             by evaluating IVU, stone size 6 mm to 20 mm,         osmolality level. The average 24-hour urinary
             23 cases in distal and 7 in proximal ureter.         total proteins in nephritic patient were 2148.6 ±
                                                                  808.7 mg and the spot urinary protein/creatinine
             A semirigid ureteroscope was introduced in           and spot urinary protein/osmolatity were 3.2332
             the ureter with the help of guide wire until the     ± 0.4293 mg/mg and 3.2418  ±    0.4393
             stone is identified through which a 365  µm          mg/mOsm respectively. There was a strong
                                                                  positive correlation of the 24-hour urinary total
             laser fiber was passed and stone was                 protein with spot urinary protein/creatinine  and
             fragmented into tiny pieces. All fragments           protein/osmolality ratios (r= 0.9846 and 0.9870,
             came out spontaneously and dormia basketery          p  =<0.001).  But in control group, these ratios
             was not required but in 4 cases. D-J stenting        did not show any correlation with 24-hour
             was done in 6 patients.                              urinary total protein. These results suggest  that
                                                                  in pediatric patients with nephrotic range of
             Neither Ureteral injury nor perforation was          proteinuria, the spot  urinary  protein/osmolality
             observed during the procedure in any cases.          ratio  can predict the 24-hour urinary total
             Stone fragmentation and extraction was easier,       protein excretion like that of  spot  urinary
             quicker and dormia basketery was not required        protein/creatinine ratios.
             except in 4 patients. Only 6 patients were
             stented.Operation time range from 15-90              289  KABIR, A.K.M.N.; KAMAL, M.
             minutes. The patients were evaluated on the          (Dept. of Pathology, Bangabandhu Sheikh  Mujib



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