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Ludipress was used in high ratio, it was found to immunoglobulin level and degree of disorder
retard the release rate more prominently. and possibility of using as a diagnostic tool for
identification of this disease.
230 AZIZ, M.A.; RAHMAN, M.M.;
MONDAL, A.K.; MUSLIM, T.; RAHMAN, 232 BAKER, M.A.; SADAT, A.F.M.N.
M.A. & QUADER, M.A. (Dept. of Chemistry, (Dept. of Pharsmacy, Asia Pacific University,
Dhaka University, Dhaka). 3-ACETOXY-6- Dhaka); RAHMAN, M.L. (ISRT, Dhaka
BENZOYLOXYAPANGAMIDE FROM University, Dhaka) ; QUSAR, M.M.A.S.
ACHYRANTHES ASPERA. Dhaka Univ. J. (Dept. of Psychiatry, BSMMU, Dhaka); HUQ,
Pharm. Sci., 2005, 4 (2), 113-116. S.M.I. (Dept. of Soil, Water and Environment,
Dhaka University, Dhaka); HOSSAIN, M.I.
3-Acetoxy-6- benzoyloxyapangamide (1) has been & HASNAT, A. (Dept. of Clinical Pharmacy
isolated from an ethyl acetate extract of the stem of and Pharmacology, Dhaka University, Dhaka).
Achyranthes aspera. The Structure of the isolated SERUM TRACE ELEMENTS IN MANIC
compound was established by modern PATIENTS. Dhaka Univ. J. Pharm. Sci., 2005,
spectroscopic techniques. The extract was found to 4 (1), 11-14.
show mild antibacterial activity against Bacillus
cereus. The serum concentration of zinc, copper,
manganese and lead in 30 manic patients and 30
231 BAKER, A.; SADAT, A.F.M.N. (Dept. human volunteers were determined by flame
of Pharmacy, Asia Pacific University, Dhaka); atomic absorption spectroscopy. It was observed
HOSSAIN, M.l.; HASNAT, A. (Dept. of that the concentration of zinc in manic patients
Clinical Pharmacy and Pharmacology, Dhaka increased significantly (P < 0.05), where as the
University, Dhaka) & ISLAM, S. N. (Institute of concentrations of copper, manganese and lead
Nurition and Food Sciences, Dhaka University, were found to be within the limit (P > 0.05).
Dhaka). IMMUNOGLOBULIN LEVELS IN These concentrations of different trace elements
MANIC PATIENTS. Dhaka Univ. J. Pharm. Sci., may have some prognostic significance for the
2005, 4 (2), 99-102. diagnosis of manic patients, but more work is
suggested to find out the exact correlation
The aim of this study was to determine the Serum between trace elements level & the degree of
immunoglobulin concentration in both manic disorder in manic patients.
patients and in healthy volunteers. The study was
conducted with 30 manic patients(24 males and 6 233 BEGUM, T.; RAHMAN, M.S.
females, aged 55.4 ± 13.0 years) age and gender (Phytochemical Research Laboratory, Dept. of
matched control subjects were enrolled. An Pharmaceutical Chemistry, Dhaka University,
enzyme-linked immunosorbeni assay (ELISA) was Dhaka). & RASHID, A. (Centre for
employed to analyze the serum immunoglobulin Biomedical Research, Dhaka University,
concentrations. IgG level was found to be 18.22± Dhaka). PHYTOCHEMICAL AND
6.42 g/l in the manic patcents. while it was 1605± BIOLOGICAL INVESTIGATIONS OF
0.51 g/l the manic patients. whereas those were PHYLLANTHUS RETICULATUS. Dhaka
5.73+1.63 g/l (P=0.034) in manic patients while
the concentrations of lgG and lgM remained Univ. J. Pharm. Sci ., 2006, 5 (1-2), 21-23.
unchanged in many psychiatric disorders
immunoglobulin level has been found to be Scopoletin (1) was isolated from the
changed significantly. This study reveals that the chloroform soluble fraction of a methanol
concentration of lgA in manic patients increased extract of the stem bark of Phyllanthus
significantly (p=0.34) which usually happens in reticulatus (Family: Euphorbiaceae). The
case of many psychiartric patients. Further petroleum ether, carbon tetrachloride and
studies are suggested with larger population to choloroform soluble fractions of this methanol
find out the correlation between extract were subjected to antimicrobial
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