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496 ANIK, A.R. (Transparency International between the protein levels. Percentage of does
Bangladesh, Dhaka) & REZA, A. (Dept. of kidded, gestation period, individual kit weight at
Animal Nutrition, Bangladesh Agricultural weaning, individual kit weight gain upto weaning
University, Mymensingh). Profitability of Rabbit and kit mortality upto weaning did not differ
Rearing in two Selected Villages of Bangladesh. significantly (P>0.05) among the levels of
Bang. J. Anim. Sci., 2006, 35 (1 & 2), 75-84. supplemental energy. However, litter size at
weaning, litter weight at weaning and total kits
Profitability of rabbit rearing and its effect on total alive at weaning differed significantly (P<0.05)
income of the farmers' households was estimated among the supplemental energy levels. The study
in this article. Gross return, return over total cost, revealed that ad libitum green grass plus
revenue cost ratio was employed here to estimate supplementary concentrate mixture containing
the profitability of rabbit farming. All the estimates 2700 kcal ME /kg DM and 16% CP was best for
of profitability showed positive results. Moreover, optimum growth and 2500 kcal ME/kg DM with
income from rabbit rearing was found to have 16% CP, is best for reproductive performance of
positive significant impact on total income of female rabbits.
farmers' household.
498 KARIM, M.M.; CARTHY, J.E.G.M.C.;
497 ISLAM, M.N. (Lion Feeds Limited, (Posttranscriptional Control Group, Dept. of
Gazipur); REZA, A. (Dept. of Animal Nutrition, Biomolecular Sciences, University of Manchester,
Bangladesh Agricultural University, Mymensingh) Institute of Science & Technology (UMIST)
& ISLAM, S. (Dept. of Animal Science, Manchester M601QD, U.K.). Repression of Cap-
BSMRAU, Salna, Gazipur). Effect of Different Dependent Translation by 4E-Binding Proteins in
Levels of Energy and Protein on Growth and Rabbit Reticulocyte Lysates. Bang. J. Microbiol.,
Reproductive Performance of Rabbits Fed Dhal 2005, 22(1), 10-14.
Grass (Hymenachne amplexicaulis) as Basal Feed.
7
Bang. J. Anim. Sci., 2007, 36 (1 & 2), 73-81. The cap structure, m GpppN, is present at the 5’
end of all eukaryotic cellular (except organellar)
An experiment was conducted for 130 days with mRNAs. Initiation of translation is mediated by the
eighteen growing female rabbits (16 to 18 weeks multi-subunit initiation factor eIF4F, which binds
age, 1300-1560 g body weight) divided into three the cap structure via its eIF4E subunit and
blocks and each block was then assigned at random facilitates the binding of mRNA to ribosome. The
to six dietary treatments in a 3 × 2 factorial design eIF4E activity is regulated in part by two
(i.e. energy 2300, 2500, 2700 kcal ME/kg DM and translational repressors, 4E-BP1 and 4E-BP2,
crude protein 14 and 16%) having three rabbits in which bind to it and prevent its assembly into
each treatment group, where dhal grass was offered eIF4F. We purified the recombinant 4 E-BP1 and
ad libitum. Dry matter intake and FCR 4E-BP2 using Escherichia coli as expression host
significantly (P<0.01) decreased with the increased and studied their ability to inhibit translation in a
levels of energy in both growth and reproduction cell-free translation system, the rabbit reticulocyte
periods. But live weight gain and GV significantly lysates. Both of the 4E-BPs inhibits translation of a
(P<0.01) increased with increasing levels of capped RNA in a dose-dependent manner under
supplemental energy in the diet. Dry matter intake, conditions when they produce no effect on
FCR and GV did not differ significantly (P>0.05) uncapped message. This result clearly indicates

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