Page 74 - Cardiac testing for coronary artery disease in potential kidney transplant recipients

Sharma 2009 (Continued)

Relevant clinical information? Yes All patients missing from the final analysis
All tests were accounted for

Uninterpretable results reported? Yes No results were reported to be uninter-
All tests pretable.

Withdrawals explained? Yes No withdrawals were reported.
All tests

Sharples 2004
Clinical features and settings Clinical features
• ESKD patients referred for coronary angiography as part of cardiac work up
before kidney transplantation
Setting
• Two inner city renal units in Royal London and St Bartholomew’s Hospital,
London, UK
Participants • Number: 18
• DM: percentage not reported
• Angina pectoris: percentage not reported
• Hypertension: percentage not reported
• Sex: 50% male
• Man age: 53.9 years (range 31 to 73 years)
• Mean time on RRT: 27.4 months (range 4 to 111 months)

Study design Cross sectional study

Target condition and reference standard(s) Coronary artery stenosis measured by coronary angiography
• CAD defined as presence of ≥ 1 coronary arteries with at least 50% stenosis.

Index and comparator tests EBCT
• Images were performed with a 100-ms scanning time and a single slice thickness
of 3 mm. 36 to 40 tomographic slices were obtained for each subject during 2 breath-
holding sessions. The degree of coronary artery calcification was calculated by
multiplying the area of each calcified lesion by a weighting factor corresponding to the
peak pixel intensity for each lesion to yield a lesion-specific calcification score. The
proximal segments of the left main stem, left anterior descending, left circumflex and
right coronary arteries were examined.

Follow-up None reported.

Notes Results reported per vessel, not per patient. Insufficient data to construct meaningful 2
x 2 table. Therefore, study did not contribute data to the meta-analysis

Table of Methodological Quality

Cardiac testing for coronary artery disease in potential kidney transplant recipients (Review) 72
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.