Page 78 - Cardiac testing for coronary artery disease in potential kidney transplant recipients

Vandenberg 1996 (Continued)

Uninterpretable results reported? Yes Yes. One MPS was technically suboptimal
All tests and was therefore not included in the anal-
ysis. Exercise ventriculography was subop-
timal in five patients and they were not in-
cluded in the analysis

Withdrawals explained? Yes All patients missing from the final analysis
All tests were accounted for

West 2000
Clinical features and settings Clinical features
• Dialysis-dependent renal transplant candidates evaluated between 1 January l993
and 1 March l995 were screened for cardiac high-risk factors (identified as those with
diabetes mellitus, previous MI, age 50 years or more cerebral and/or peripheral vascular
disease, CHF, class I or II angina (Canadian Cardiovascular Society classification), and
dialysis dependency of more than 5 years).
Setting
• Geisinger Medical Center, Danville, Pennsylvannia, USA

Participants • Number: 33
• DM: percentage not reported
• Angina pectoris or IHD: percentage not reported
• Hypertension: percentage not reported
• Sex: not reported

Study design Cohort study

Target condition and reference standard(s) Coronary artery stenosis measured by coronary angiography
• CAD was defined as the presence of one or more coronary arteries with 70% or
greater diameter stenosis, or greater than 50% in left main coronary artery.

Index and comparator tests DSE
• DSE was performed the day after dialysis to avoid hypertensive blood pressure
response from volume overload. A standardised DSE protocol was used. DSE findings
were graded as negative if normal wall motion was present and positive when:
◦ CAD: fixed, inducible, or mixed segmental wall motion abnormalities
◦ Cardiomyopathy: diffuse wall motion abnormalities or
◦ Primary valvular heart disease: severe aortic stenosis, aortic insufficiency,
mitral stenosis, or mitral regurgitation secondary to primary leaflet abnormalities were
present

Follow-up Patients were followed up for an unspecified time.

Notes
Table of Methodological Quality

Cardiac testing for coronary artery disease in potential kidney transplant recipients (Review) 76
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.