Page 435 - 16Neonatal Jaundice_compressed
P. 435

Neonatal jaundice


 Bibliographic   Study Type &   Number of   Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
 Information   Evidence Level   Patients/Characteristics   (E:C)   (Mean:SD: N)
 Mean BW: 1412 ± 256 g   phototherapy.
 Mean age at entry to study:
 120 ± 72 hours
 Mean TSB: Not reported
 Author:   Methodology:   N:   Babies with hyperbilirubinaemia   ET:   Mean change in TEWL
                                       2
 Wananukul S   Comparative study   80 (40 with hyperbilirubinaemia  received conventional phototherapy in   Group 1:   PT: 1.2 ± 3.9 g/m /h
       who received phototherapy and  open cribs. Phototherapy consisted of 6  Group 2:
                                          2
 Year:   Blinding:   40 healthy controls)   white and 2 blue fluorescent bulbs in a      Control: 0.2 ± 0.9 g/m /h
 2001   None      plexiglass-bottomed box 30cm above   Mortality:
       Inclusion:   the baby. Irradiance was   Group 1:   TEWL retuned to pre-phototherapy levels within 1 hour of
 Country:   Randomisation:   Term babies   10 microwatt/cm² per nm.   Group 2:   discontinuation of phototherapy
 Thailand   None
       Exclusion:   TEWL was measured with a Tewameter
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 ID:     Evidence level:   None   TM 2/0 (Courage & Khazama) and
 2 -      measurements were taken at chest,
    Demographics:   interscapular and buttocks of the baby.
 Gender (M/F): 44/36   Measurements were taken before
 Mean GA: 39.0 ± 1.2 weeks   phototherapy and repeated at 30 minutes
 and 6 hours during phototherapy.
 Mean BW: 3166 ± 435 g
 Mean age at entry to study: Not
 reported
 Mean TSB: Not reported
 Author:   Methodology:   N:   All babies were nursed naked, except      Mean change in TEWL
 Maayan-Metzeger A  Case series   31   for eye pads, in incubators and received   PT: 4.3 ± 4.7 g/m /h
                                       2
          phototherapy..
 Year:   Blinding:   Inclusion:
 2001   None   Preterm with   Conventional phototherapy consisted of
       hyperbilirubinaemia   (Air Shields Micro-Lite) Light range
 Country:   Randomisation:      was 400 – 500 nm.
 Israel   None   Exclusion:
       Respiratory distress,   TEWL was measured usinga combined
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 ID:     Evidence level:   Sepsis,   Tewameter and corneometer (Courage
 3    Need for ventilatory support   and Khazka)

 Demographics:   TEWL was measure in seven body
 Gender (M/F): 15/16   areas; forehead, upper back, cubital
 Mean GA: 31.2 weeks   fossa, palms, abdomen, soles, and
 Mean BW: 1447 g   inguinal region.
 Mean age at entry to study:
 106 hours   Measurement were taken before start of
 Mean TSB: Not reported   phototherapy and repeated during
 phototherapy (at least 4 and up to
 24 hours)
 Author:   Methodology:   N:   Group 1:   Patent Ductus Arteriosus
 Rosenfeld W   RCT   74   Phototherapy   Group 1: 23/38
             Group 2: 11/36


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