Page 430 - 16Neonatal Jaundice_compressed
P. 430

Neonatal jaundice


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                             1 -            Babies who received antibiotics  All babies were treated in intensive care
                                                                  incubators.
                                            Demographics:
                                            Gender (M/F): 62/39   Conventional phototherapy consisted of
                                            Median GA: 40 weeks   a Drager 76 unit equipped with 6 blue
                                            Mean BW: Not reported   standard fluorescent lights (light range
                                            Mean age at entry to study: Not  410 – 520 nm)
                                            reported
                                            Mean TSB:             In the second group the four outer walls
                                            243 ± 28 micromol/litre   of the incubator were draped in white
                                                                  cloth

                                                                  The halide phototherapy consisted of a
                                                                  Drager 8000 halide lamp (light range
                                                                  400 – 580 nm)

                                                                  All phototherapy units were 34cm
                                                                  above the mattress.

                                                                  Babies were naked except for a bikini
                                                                  diaper and blindfolds and were their
                                                                  position was changed every 4 hours.
                                                                  Phototherapy could be interrupted for
                                                                  nursing care and feedings.

                                                                  Babies received oral feedings of either
                                                                  mother’s milk or adapted formula and
                                                                  dextrose solution.
              Author:        Methodology:   N:                    Group 1:                                     Mean change in TsB (4 hours)
              Djokomuljanto S   RCT         100                   Conventional phototherapy                    Group 1: -4 ± 24 micromol/litre

              Year:          Blinding:      Inclusion:            Group 2:                                     Group 2: -28 ± 25 micromol/litre
              2006           Investigators blinded  Term babies with uncomplicated  Conventional phototherapy + white
                             to allocation   jaundice requiring phototherapy  curtains
              Country:
              Malaysia       Randomisation:   Exclusion:          Conventional phototherapy consisted of
                             Block randomisation  TsB approaching criteria for   Phoenix Medical Systems unit of 6
                190
              ID:                           exchange transfusion   compact blue fluorescent lamps 45 cm
                             Evidence level:                      above the baby.
                             1 +            Demographics:
                                            Gender (M/F): 56/44   Curtains were hung on both sides if the
                                            Mean GA: Not reported   phototherapy unit.
                                            Mean BW: Not reported
                                            Mean age at entry to study:
                                            105 ± 35 hours
                                            Mean TSB:
                                            264 ± 59 micromol/litre



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