Page 434 - 16Neonatal Jaundice_compressed
P. 434

Neonatal jaundice


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                                            Mean BW: 1412 ± 256 g   phototherapy.
                                            Mean age at entry to study:
                                            120 ± 72 hours
                                            Mean TSB: Not reported
              Author:        Methodology:   N:                    Babies with hyperbilirubinaemia   ET:        Mean change in TEWL
                                                                                                                           2
              Wananukul S    Comparative study   80 (40 with hyperbilirubinaemia  received conventional phototherapy in   Group 1:   PT: 1.2 ± 3.9 g/m /h
                                            who received phototherapy and  open cribs. Phototherapy consisted of 6  Group 2:
                                                                                                                              2
              Year:          Blinding:      40 healthy controls)   white and 2 blue fluorescent bulbs in a      Control: 0.2 ± 0.9 g/m /h
              2001           None                                 plexiglass-bottomed box 30cm above   Mortality:
                                            Inclusion:            the baby. Irradiance was   Group 1:          TEWL retuned to pre-phototherapy levels within 1 hour of
              Country:       Randomisation:   Term babies         10 microwatt/cm² per nm.   Group 2:          discontinuation of phototherapy
              Thailand       None
                                            Exclusion:            TEWL was measured with a Tewameter
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              ID:            Evidence level:   None               TM 2/0 (Courage & Khazama) and
                             2 -                                  measurements were taken at chest,
                                            Demographics:         interscapular and buttocks of the baby.
                                            Gender (M/F): 44/36   Measurements were taken before
                                            Mean GA: 39.0 ± 1.2 weeks   phototherapy and repeated at 30 minutes
                                                                  and 6 hours during phototherapy.
                                            Mean BW: 3166 ± 435 g
                                            Mean age at entry to study: Not
                                            reported
                                            Mean TSB: Not reported
              Author:        Methodology:   N:                    All babies were nursed naked, except         Mean change in TEWL
              Maayan-Metzeger A  Case series   31                 for eye pads, in incubators and received     PT: 4.3 ± 4.7 g/m /h
                                                                                                                           2
                                                                  phototherapy..
              Year:          Blinding:      Inclusion:
              2001           None           Preterm with          Conventional phototherapy consisted of
                                            hyperbilirubinaemia   (Air Shields Micro-Lite) Light range
              Country:       Randomisation:                       was 400 – 500 nm.
              Israel         None           Exclusion:
                                            Respiratory distress,   TEWL was measured usinga combined
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              ID:            Evidence level:   Sepsis,            Tewameter and corneometer (Courage
                             3              Need for ventilatory support   and Khazka)

                                            Demographics:         TEWL was measure in seven body
                                            Gender (M/F): 15/16   areas; forehead, upper back, cubital
                                            Mean GA: 31.2 weeks   fossa, palms, abdomen, soles, and
                                            Mean BW: 1447 g       inguinal region.
                                            Mean age at entry to study:
                                            106 hours             Measurement were taken before start of
                                            Mean TSB: Not reported   phototherapy and repeated during
                                                                  phototherapy (at least 4 and up to
                                                                  24 hours)
              Author:        Methodology:   N:                    Group 1:                   Patent Ductus Arteriosus
              Rosenfeld W    RCT            74                    Phototherapy               Group 1: 23/38
                                                                                             Group 2: 11/36


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