Page 431 - 16Neonatal Jaundice_compressed
P. 431

Neonatal jaundice


 Bibliographic   Study Type &   Number of   Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
 Information   Evidence Level   Patients/Characteristics   (E:C)   (Mean:SD: N)
 1 -   Babies who received antibiotics  All babies were treated in intensive care
        incubators.
 Demographics:
 Gender (M/F): 62/39   Conventional phototherapy consisted of
 Median GA: 40 weeks   a Drager 76 unit equipped with 6 blue
 Mean BW: Not reported   standard fluorescent lights (light range
 Mean age at entry to study: Not  410 – 520 nm)
 reported
 Mean TSB:   In the second group the four outer walls
 243 ± 28 micromol/litre   of the incubator were draped in white
 cloth

 The halide phototherapy consisted of a
 Drager 8000 halide lamp (light range
 400 – 580 nm)

 All phototherapy units were 34cm
 above the mattress.

 Babies were naked except for a bikini
 diaper and blindfolds and were their
 position was changed every 4 hours.
 Phototherapy could be interrupted for
 nursing care and feedings.

 Babies received oral feedings of either
 mother’s milk or adapted formula and
 dextrose solution.
 Author:   Methodology:   N:   Group 1:      Mean change in TsB (4 hours)
 Djokomuljanto S   RCT   100   Conventional phototherapy   Group 1: -4 ± 24 micromol/litre

 Year:   Blinding:   Inclusion:   Group 2:   Group 2: -28 ± 25 micromol/litre
 2006   Investigators blinded  Term babies with uncomplicated  Conventional phototherapy + white
    to allocation   jaundice requiring phototherapy  curtains
 Country:
 Malaysia   Randomisation:   Exclusion:   Conventional phototherapy consisted of
    Block randomisation  TsB approaching criteria for   Phoenix Medical Systems unit of 6
 190
 ID:        exchange transfusion   compact blue fluorescent lamps 45 cm
 Evidence level:      above the baby.
 1 +   Demographics:
     Gender (M/F): 56/44   Curtains were hung on both sides if the
 Mean GA: Not reported   phototherapy unit.
 Mean BW: Not reported
 Mean age at entry to study:
 105 ± 35 hours
 Mean TSB:
 264 ± 59 micromol/litre



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