Page 429 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
1973 Not reported Birthweight < 2500 g Group 3: 60 ± 42 micromol/litre
Group 2:
Country: Randomisation: Exclusion: Early phototherapy – Intermittent – Group 4: 147 ± 57 micromol/litre
USA Not reported Positive Coombs test, 12 hours daily for 4 days
Potential ABO incompatibility,
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ID: Evidence level: sepsis Group 3:
1 - Early phototherapy – Continuous –
Demographics: 24 hours daily for 4 days
Gender (M/F) : 39/30
Mean GA: 34.2 ± 3.8 weeks Group 4:
No treatment
Mean BW: 1860 ± 344 g
Age at entry to study:
< 24 hours Phototherapy consisted of 8 blue
fluorescent lamps (200 – 300 foot
Mean TSB: Not reported candles) 40 cm above the baby
Author: Methodology: N: Group 1: TEWL – at 5 hours
Wananukul S RCT 40 Clear topical ointment 3.0 ml Group 1: 7.5 ± 1.5 g/m /h
2
(Vaseline:liquid paraffin = 1:1)
2
Year: Blinding: Inclusion: Group 2: 8.9 ± 1.6 g/m /h
2002 Not reported Preterm babies requiring Group 2:
phototherapy for No ointment
Country: Randomisation: hyperbilirubinaemia
Thailand Nor reported All babies were placed in incubators.
Exclusion:
ID: Evidence level: Skin disease, Ointment was applied to the whole
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1 - Respiratory distress body, measurements taken from upper
arms, back and legs.
Demographics:
Gender (M/F) : 22/18 Evaporation rate was measured by a
Mean GA: 33.1 ± 2.6 weeks method based on the determination of
the water vapour pressure gradient in
Mean BW: 1444 ± 196 g the air layer closed to the skin surface.
Mean age at entry to study: Not (Tewameter TM 210)
reported
Mean TSB:
171 ± 39 micromol/litre
Author: Methodology: N: Group 1: Mean change in TsB (24 hours)
Eggert P RCT 101 Conventional Phototherapy Group 1: -56 ± 26 micromol/litre

Year: Blinding: Inclusion: Group 2: Group 2: -80 ± 27 micromol/litre
1988 Not reported Uncomplicated Conventional Phototherapy + white Group 3: -55 ± 22 micromol/litre
hyperbilirubinaemia curtains
Country: Randomisation:
Germany Not reported Exclusion: Group 3:
Age < 40 hours with ABO or Rh Halide Phototherapy
ID: Evidence level: incompatibility,
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