Page 427 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)

Author: Methodology: N: Group 1: ET: Max TSB:
Curtis-Cohen M RCT 22 Early Phototherapy Group 1: 0/11 Group 1: 112 ± 27 micromol/litre
Group 2: 0/11
Year: Blinding: Inclusion: Group 2: Group 2: 123 ± 20 micromol/litre
1985 Not reported Preterm babies Delayed start of treatment – Mortality:
Phototherapy started at TsB Group 1: 0/11
Country: Randomisation: Exclusion: > 85.5micromol/litre Group 2: 0/11
USA Not reported Haemolytic disease, Phototherapy consisted of a broad
Direct hyperbilirubinaemia, spectrum white light from a tungsten-
149
ID: Evidence level: sepsis halogen lamp in a Model 1400
1 - phototherapy unit.
Demographics:
Gender (M/F) : Not reported Irradiance was maintained at
2
Mean GA: 27.4 ± 1.4 weeks 12microW/cm /nm at 450nm
Mean BW: 858 ± 214 g
Mean age at entry to study: Not
reported
Mean TSB: Not reported
Author: Methodology: N: Group 1: ET: Max TSB:
Leite M RCT 81 Early Phototherapy Group 1: 0/35 Group 1: 113 ± 49 micromol/litre
Group 2: 0/35
Year: Blinding: Inclusion: Group 2: Group 2: 147 ± 36 micromol/litre
2004 Not reported Birthweight < 2000 g Phototherapy at TsB
≥ 136.8micromol/litre
Country: Randomisation: Exclusion:
Brazil Not reported Haemolysis,
G6PD deficiency, Phototherapy discontinued at TsB <
150
ID: Evidence level: Malformations, 85.5micromol/litre
1 - Intestinal obstructions,
Cholestasis, congenital Phototherapy consisted of fanem Mod
infections, 007 units equipped with 7 Philips
Maternal or neonatal use of fluorescent lamps (special blue), 400 –
Phenobarbital, TCB 540 nm
> 256.5micromol/litre
Average irradiance was
2
Demographics: 14.4microW/cm /nm
Gender (M/F) : 37/33
Mean GA: Not reported
Mean BW: Not reported
Mean age at entry to study: Not
reported
Mean TSB: Not reported
Author: Methodology: N: Group 1: Max TSB:
Maurer H RCT 69 Agar – 125mg in first 4ml of formula Group 1: 118 ± 40 micromol/litre
beginning at 18 hours and continued at
Year: Blinding: Inclusion: 3 hourly intervals for 4 days Group 2: 108 ± 36 micromol/litre

286