Page 422 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
Author: Methodology: N: Group 1: Mean duration of phototherapy
Vogl T RCT 76 Continuous Phototherapy Group 1: 64 ± 50 hours

Year: Blinding: Inclusion: Group 2: Group 2: 57 ± 45 hours
1978 Not reported Birthweight between 1200 and Intermittent Phototherapy – 15 minutes Group 3: 79 ± 40 hours
2400gms, on – 15 minutes off
Country: Randomisation: TSB > 137 micromol/litre Group 4: 80 ± 50 hours
USA Not reported Group 3:
Exclusion: Intermittent Phototherapy – 15 minutes
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ID: Evidence level: Haemolytic anaemia, on – 30 minutes off
1 - Positive Coombs tests,
Respiratory distress syndrome Group 4:
Intermittent Phototherapy – 15 minutes
Demographics: on – 60 minutes off
Gender (M/F) :
Mean GA: 34.7 ± 2.0 weeks Therapy was discontinued when TSB
< 137 micromol/litre on two successive
Mean BW: 1836 ± 299 gms occasions
Age at entry to study
56.8 ± 10.8 hours
Mean TSB:
150 ± 19 micromol/litre
Author: Methodology: N: Group 1: Prurient eye discharge Mean duration of phototherapy
Fok T RCT 203 Eye patches Group 1: 23/102 Group 1: 67.2 ± 33.6 hours
Group 2: 9/101
Year: Blinding: Inclusion: Group 2: Group 2: 64.5 ± 26.6 hours
1995 Not reported Gestational age > 35 weeks, Headbox Features of Conjunctivitis
Birthweight > 2300 gms, Group 1: 13/102
Country: Randomisation: Eye patches were obtained Group 2: 2/101 HC Professional satisfaction:
Hong Kong Computer generated Exclusion: commercially, were removed during 76 (70.4%) of nurse preferred the headbox while 17 (15.7%)
random numbers Other systemic illness, feeding and were replaced daily preferred the eye patches.
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ID: Eye infection,
Evidence level: Haemolysis, Headbox consisted of an opaque plastic
1 + Treatment with antibiotics, box (20 x 20 x 16cm). Holes were used
History of infection, for ventilation.

Demographics:
Gender (M/F): 106/97
Mean GA: 38.6 ± 2.56 weeks
Mean BW: 3087 ± 611 gms
Age at entry to study
89.5 ± 27.6 hours
Mean TSB:
258 ± 27 micromol/litre
Author: Paludetto R Methodology: N: Group 1: Mean duration of phototherapy

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