Page 419 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)

Babies wore eye patches

Phototherapy was continuous except for
breaks for feeding etc

Phototherapy discontinued at a steady
rate and reached TSB <
137 micromol/litre
Author: Shinwell E Methodology: N: 32 Group 1: ET: Mean duration of phototherapy
RCT Supine position Group 1: 0/16 Group 1: 28 ± 9 hours
Year: Inclusion: Group 2: 1/16
2002 Blinding: Full-term, Group 2: Group 2: 40 ± 15 hours
Not reported Birthweight > 2500gms, Changing positions
Country: TSB > 308 micromol/litre Rebound jaundice: Mean change in TSB:
Israel Randomisation: Not reported Group 1: -114 ± 23 micromol/litre
Not reported but Exclusion: All babies received identical
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ID: sealed, opaque Congenital malformation phototherapy for periods of 150 minutes Treatment failure: Group 2: -108 ± 11 micromol/litre
envelopes used followed by 30 minute breaks for Group 1: 0/16
Demographics: feeding and routine nursing care. Group 2: 1/16
Evidence level: Gender (M/F): 8/22 Babies in changing position group were
1 + Mean GA: 38 ± 1 weeks alternated between supine and prone
Mean BW: 3500 ± 478 gms Phototherapy discontinued after two
Age at entry to study consecutive measurements TSB
104.2 ± 33.7 hours < 239 micromol/litre
Mean TSB:
320 ± 17 micromol/litre
Author: Methodology: N: 51 Group 1: Mean duration of phototherapy
Chen C RCT Supine position Group 1: 53.3 ± 17.9 hours
Inclusion:
Year: Blinding: TSB > 256 micromol/litre, Group 2: Group 2: 52.8 ± 20.2 hours
2002 Not reported Absence of blood group Changing position
incompatibility, Mean change in TSB:
Country: Randomisation: Normal G6PD status, Group 1: -128 ± 54 micromol/litre
Taiwan Not reported but Haemoglobin > 14g/dl Phototherapy initiated at TSB
sealed envelopes ≥ 256 micromol/litre and discontinued Group 2: -126 ± 45 micromol/litre
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ID: used. Exclusion: at TSB < 171 micromol/litre
Congenital anomalies,
Evidence level: Significant bruising, Babies in changing position group were
1 + Large cephalhematoma alternated between supine and prone
every 120 minutes
Demographics:
Gender (M/F): 19/32
Mean GA: 38.2 ± 1.14 weeks
Mean BW:3137 ± 384 gms

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