Page 414 - 16Neonatal Jaundice_compressed
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Neonatal jaundice


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                             Evidence level:                      phototherapy unit.
                             1 -            Demographics:                                                      Study 2 – Preterm
                                            Gender (M/F): Not reported                                         Mean duration of phototherapy
                                            Mean GA: 38.9 ± 0.14 weeks                                         Group 1: 53.29 ± 5.9 hours
                                            Mean BW: 3394 ± 43 gms                                             Group 2: 53.26 ± 5.52 hours
                                            Age at entry to study
                                            101.8 ± 4.32 hours                                                 Mean change in TSB:
                                            Mean TSB:                                                          Group 1: -34 ± 6 micromol/litre
                                            286 ± 60 micromol/litre                                            Group 2: -38 ± 8 micromol/litre


                                            Study 2: Preterm

                                            N: 62

                                            Inclusion:
                                            Idiopathic jaundice

                                            Exclusion:
                                            Haemolytic jaundice

                                            Demographics:
                                            Gender (M/F): Not reported
                                            Mean GA: 34.6 ± 0.36 weeks
                                            Mean BW: 2361 ± 102 gms
                                            Age at entry to study
                                            85.6 ± 5.52 hours
                                            Mean TSB:
                                            239 ± 16 micromol/litre
              Author: Amato M   Methodology:   N: 30              Group 1:                   ET:               Mean duration of phototherapy
                             RCT                                  Blue Phototherapy          Group 1: 0/15     Group 1: 34 ± 10 hours
              Year:                         Inclusion:                                       Group 2: 0/15
              1991           Blinding:      Idiopathic hyperbilirubinaemia  Group 2:                           Group 2: 70 ± 23 hours
                             Not reported   TSB ≥ 250 micromol/litre   Green Phototherapy    Rebound jaundice:
              Country:                                                                       Group 1: 12/15    Mean change in TSB:
              Switzerland    Randomisation:   Exclusion:          Phototherapy consisted of either blue or  Group 2: 3/15   Group 1: -157 ± 22 micromol/litre
                             Random numbers   Perinatal asphyxia,   green fluorescent tubes 30cm above the
                163
              ID:            table          Apgar < 4 at 1 minute and < 6 at  mattress. The baby was placed naked,      Group 2: -154 ± 31 micromol/litre
                                            5 minutes,            except for eye patches and gonadal
                             Evidence level:   Signs of haemolytic disease,   protection, on a Plexiglas surface.
                             1 +            secondary hyperbilirubinaemia
                                                                  Light spectral range of green tubes was
                                            Demographics:         350–650 nm and 300–600 for the blue
                                            Gender (M/F): 13/17   tubes


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