Page 409 - 16Neonatal Jaundice_compressed
P. 409

Appendix H: Evidence tables


 Bibliographic   Study Type &   Number of   Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
 Information   Evidence Level   Patients/Characteristics   (E:C)   (Mean:SD: N)
    Computer generated      PTL 68–1) units equipped with 3   Group 2: -44 ± 46 micromol/litre
 143
 ID:        Exclusion:   halogen quartz bulbs. Irradiance was 5–
 Evidence level:   None reported   6 microW/cm /nm.
 2
 1 +
     Demographics:   LED phototherapy consisted of 6
 Gender (M/F): Not reported   focussed arrays each with 100 3-mm
 Mean GA: Not reported   blue LED’s. Unit was placed 50cm
 Mean BW: Not reported   above the baby, to achieve an irradiance
 Age at entry to study   2
 Not reported   of 5–6microW/cm /nm.
 Mean TSB:
 251 ± 77 micromol/litre   All babies were placed in a crib and
 were naked except for diapers and eye
 coverings.
 Author: Seidman D   Methodology:   N: 114   Group 1:   ET:   Mean duration of phototherapy
    RCT      Conventional phototherapy   Group 1: 0/57   Group 1: 35.4 ± 20.2 hours
 Year:      Inclusion:      Group 2: 0/25
 2003   Blinding:   AAP criteria for phototherapy,   Group 2:   Group 3: 0/22   Group 2: 31.6 ± 19.6 hours
    Not reported      LED phototherapy - Blue      Group 3: 39.2 ± 25.5 hours
 Country:      Exclusion:      Erythema:
 Israel   Randomisation:   Not reported   Group 3:   Group 1: 0/57     Mean change in TSB:
    Computer generated      LED Phototherapy - Blue-Green   Group 2: 0/25
 144
 ID:        Demographics:      Group 3: 0/22   Group 1: -44 ± 33 micromol/litre
 Evidence level:   Gender (M/F): Not reported   Conventional phototherapy (Air Shields     Group 2: -39 ± 46 micromol/litre
 1 +   Mean GA: 39.5 ± 1.5 weeks   Micro-lites PTL 68–1) units equipped      Group 3: -41 ± 48 micromol/litre
     Mean BW: Not reported   with 3 halogen quartz bulbs. Irradiance
 2
 Age at entry to study   was 5–6 microW/cm /nm.
 53.9 ± 37.8 hours     Blue LED phototherapy consisted of 6
 Mean TSB:   focussed arrays each with 100 3-mm
 251 ± 73 micromol/litre   blue LED’s. Peak wavelength was
 459nm with a half spectral width of
 22nm. Unit was placed 50cm above the
 baby, to achieve an irradiance of 5–
 2
 6microW/cm /nm.

 Blue-Green LED phototherapy
 consisted of 6 focussed arrays each with
 100 3-mm blue-green LED’s. Peak
 wavelength was 505nm with a half
 spectral width of 38nm. Unit was placed
 50cm above the baby, to achieve an
 2
 irradiance of 5–6microW/cm /nm.


 All babies were placed in open cribs and
 were naked except for diapers and eye


                                                                 277
   404   405   406   407   408   409   410   411   412   413   414