Page 408 - 16Neonatal Jaundice_compressed
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Appendix H: Evidence tables


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                             Computer generated                   PTL 68–1) units equipped with 3              Group 2: -44 ± 46 micromol/litre
                143
              ID:                           Exclusion:            halogen quartz bulbs. Irradiance was 5–
                             Evidence level:   None reported      6 microW/cm /nm.
                                                                           2
                             1 +
                                            Demographics:         LED phototherapy consisted of 6
                                            Gender (M/F): Not reported   focussed arrays each with 100 3-mm
                                            Mean GA: Not reported   blue LED’s. Unit was placed 50cm
                                            Mean BW: Not reported   above the baby, to achieve an irradiance
                                            Age at entry to study            2
                                            Not reported          of 5–6microW/cm /nm.
                                            Mean TSB:
                                            251 ± 77 micromol/litre   All babies were placed in a crib and
                                                                  were naked except for diapers and eye
                                                                  coverings.
              Author: Seidman D   Methodology:   N: 114           Group 1:                   ET:               Mean duration of phototherapy
                             RCT                                  Conventional phototherapy   Group 1: 0/57    Group 1: 35.4 ± 20.2 hours
              Year:                         Inclusion:                                       Group 2: 0/25
              2003           Blinding:      AAP criteria for phototherapy,   Group 2:        Group 3: 0/22     Group 2: 31.6 ± 19.6 hours
                             Not reported                         LED phototherapy - Blue                      Group 3: 39.2 ± 25.5 hours
              Country:                      Exclusion:                                       Erythema:
              Israel         Randomisation:   Not reported        Group 3:                   Group 1: 0/57       Mean change in TSB:
                             Computer generated                   LED Phototherapy - Blue-Green   Group 2: 0/25
                144
              ID:                           Demographics:                                    Group 3: 0/22     Group 1: -44 ± 33 micromol/litre
                             Evidence level:   Gender (M/F): Not reported   Conventional phototherapy (Air Shields     Group 2: -39 ± 46 micromol/litre
                             1 +            Mean GA: 39.5 ± 1.5 weeks   Micro-lites PTL 68–1) units equipped      Group 3: -41 ± 48 micromol/litre
                                            Mean BW: Not reported   with 3 halogen quartz bulbs. Irradiance
                                                                               2
                                            Age at entry to study   was 5–6 microW/cm /nm.
                                            53.9 ± 37.8 hours       Blue LED phototherapy consisted of 6
                                            Mean TSB:             focussed arrays each with 100 3-mm
                                            251 ± 73 micromol/litre   blue LED’s. Peak wavelength was
                                                                  459nm with a half spectral width of
                                                                  22nm. Unit was placed 50cm above the
                                                                  baby, to achieve an irradiance of 5–
                                                                          2
                                                                  6microW/cm /nm.

                                                                  Blue-Green LED phototherapy
                                                                  consisted of 6 focussed arrays each with
                                                                  100 3-mm blue-green LED’s. Peak
                                                                  wavelength was 505nm with a half
                                                                  spectral width of 38nm. Unit was placed
                                                                  50cm above the baby, to achieve an
                                                                                    2
                                                                  irradiance of 5–6microW/cm /nm.


                                                                  All babies were placed in open cribs and
                                                                  were naked except for diapers and eye


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