Page 411 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
coverings.
Author: Methodology: N: 88 Group 1: ET: Mean duration of phototherapy
Martins B RCT Conventional Phototherapy Group 1: 0/44 Group 1: 63.8 ± 37 hours
Inclusion: Group 2: 0/44
Year: Blinding: Need for phototherapy Group 2: Group 2: 36.8 ± 21 hours
2007 Not reported according to birthweight LED phototherapy Erythema:
Group 1: 0/44 TSB levels – change
Country: Randomisation: Exclusion: Conventional phototherapy consisted of Group 2: 0/44 24 hours
Brazil Not reported Direct bilirubin a single quartz-halogen lamp, with a Group 1: -22 ± 25 micromol/litre
> 34 micromol/litre dichroic reflector, positioned 50cm from Treatment failure:
158
ID: Evidence level: Haemolytic jaundice, the baby and illuminating a circle of Group 1: 0/44 Group 2: -50 ± 26
1 - Ecchymosis, 18cm diameter. Group 2: 0/44 micromol/litre
Malformations, Mean irradiance was
2
Congenital infection 21 ± 6microW/cm /nm

Demographics: LED phototherapy consisted of the
Gender (M/F):58/30 Super LED system positioned 30cm
Mean GA: 33.6 ± 1.9 weeks from the patient and illuminating an
Mean BW: 1998 ± 541 gms elliptical area of 38cm x 27cm diameter.
Age at entry to study Mean irradiance was
2
68.1 ± 25.5 hours 37 ± 9microW/cm /nm
Mean TSB: Phototherapy discontinued when TSB
179 ± 38 micromol/litre levels decreased 30% from original
levels

Treatment was considered to have failed
if TSB continued to rise and reached a
level 30% below TSB levels required
for exchange transfusion.

Author: Ebbesen F Methodology: N: 141 Group 1: ET: Mean change in TSB:
RCT Blue phototherapy Group 1: 0/69 Group 1: -78 ± 31 micromol/litre
Year: Inclusion: Group 2: 0/72
2007 Blinding: Preterm infants (28 – Group 2: Group 2: -92 ± 31 micromol/litre
Not reported 36.6 weeks), Turquoise phototherapy
Country: Age > 24 hours,
Denmark Randomisation: No previous phototherapy,
Not stated but sealed Non-haemolytic Treatment duration was fixed (24 hours)
160
ID: envelopes used hyperbilirubinaemia
Phototherapy consisted of either 8 blue
Evidence level: Exclusion: fluorescent lamps (20 W, 60 x 3.7cm)
1 + Not reported 41 cm above the baby or 8 turquoise
fluorescent lamps (18 W, 60 x 2.6cm)

Demographics: 41 cm above the baby. Distance from
Gender (M/F): 80/61 baby was different to ensure irradiance
was identical in both groups
278