Page 407 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
2
Mean GA: 32.0 ± 0.54 weeks 35microW/cm /nm.
Mean BW: 1614 ± 140 gms Baby was nursed in an open cot or
Age at entry to study isolette and turned at regular intervals
56.6 ± 37.0 hours from prone to supine positions. Eyes
Mean TSB: Not reported pads were used for babies < 1500gms.
Author: Methodology: N: 31 Group 1: ET: Mean duration of phototherapy
Bertini G RCT Conventional phototherapy Group 1: 0/14 Group 1: 38.7 ± 5.0 hours
Inclusion: Group 2: 0/17
Year: Blinding: TSB ≥ 171 micromol/litre, Group 2: Group 2: 34.0 ± 12.0 hours
2008 Not reported Gestational ages < 34 weeks, LED Phototherapy
Age < 7days, TSB levels – change
Country: Randomisation: Did not require respiratory Conventional phototherapy (Photo- Group 1: -62 ± 24 micromol/litre
Italy Not reported but support, Therapie 800) incorporating a metal
sealed envelopes used Clinically stable vapour discharge blue lamp with two Group 2: -55 ± 5 micromol/litre
159
ID: filters (an infrared cut-off filter and a :
Evidence level: Exclusion: Plexiglas ultraviolet cut-off filter). 20
1+ Malformations, cm above the baby.
Perinatal asphyxia,
Patent ductus arteriosus, LED phototherapy (Natus NeoBlue
intracranial haemorrhage, system). Light range 450–470nm
hypotension, spectrum. Irradiance was at the
Hypertension, intensive setting at 30–
Infection, 35 microW/cm /nm. Unit was placed
2
Anemia (venous Hb< 10g/dl), 30cm above the baby.
Polycythemia (venous
Hb> 22 g/dl), All babies were placed in incubators
Infants receiving cardiovascular with a thermo-monitoring system to
drugs. maintain a normal body temperature
o
Demographics: (36.5 C) at a relative humidity of 60%.
Gender (M/F): Not reported Babies received full enteral feeding with
Mean GA: 30.7 ± 2.0 weeks human milk.
Babies were naked except for eye
Mean BW: 1192 ± 238 gms patches and were in a supine position.
Age at entry to study
64.4 ± 15.2 hours Phototherapy discontinued at
< 145 micromol/litre
Mean TSB:
200 ± 16 micromol/litre
Author: Seidman D Methodology: N: 69 Group 1: ET: Mean duration of phototherapy
RCT Conventional phototherapy Group 1: 0/35 Group 1: 32.0 ± 17.0 hours
Year: Inclusion: Group 2: 0/34
2000 Blinding: Full-term (Gestational age Group 2: Group 2: 31.0 ± 17.0 hours
Open label study > 37 weeks), LED phototherapy
Country: Jaundice according to AAP Mean change in TSB:
Israel Randomisation: criteria for phototherapy Conventional phototherapy (Micro-lites Group 1: -44 ± 58 micromol/litre

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