Page 415 - 16Neonatal Jaundice_compressed
P. 415

Neonatal jaundice


 Bibliographic   Study Type &   Number of   Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
 Information   Evidence Level   Patients/Characteristics   (E:C)   (Mean:SD: N)
 Evidence level:      phototherapy unit.
 1 -   Demographics:       Study 2 – Preterm
     Gender (M/F): Not reported   Mean duration of phototherapy
 Mean GA: 38.9 ± 0.14 weeks   Group 1: 53.29 ± 5.9 hours
 Mean BW: 3394 ± 43 gms    Group 2: 53.26 ± 5.52 hours
 Age at entry to study
 101.8 ± 4.32 hours        Mean change in TSB:
 Mean TSB:                 Group 1: -34 ± 6 micromol/litre
 286 ± 60 micromol/litre   Group 2: -38 ± 8 micromol/litre


 Study 2: Preterm

 N: 62

 Inclusion:
 Idiopathic jaundice

 Exclusion:
 Haemolytic jaundice

 Demographics:
 Gender (M/F): Not reported
 Mean GA: 34.6 ± 0.36 weeks
 Mean BW: 2361 ± 102 gms
 Age at entry to study
 85.6 ± 5.52 hours
 Mean TSB:
 239 ± 16 micromol/litre
 Author: Amato M   Methodology:   N: 30   Group 1:   ET:   Mean duration of phototherapy
    RCT      Blue Phototherapy   Group 1: 0/15   Group 1: 34 ± 10 hours
 Year:      Inclusion:      Group 2: 0/15
 1991   Blinding:   Idiopathic hyperbilirubinaemia  Group 2:      Group 2: 70 ± 23 hours
    Not reported   TSB ≥ 250 micromol/litre   Green Phototherapy   Rebound jaundice:
 Country:            Group 1: 12/15   Mean change in TSB:
 Switzerland   Randomisation:   Exclusion:   Phototherapy consisted of either blue or  Group 2: 3/15   Group 1: -157 ± 22 micromol/litre
    Random numbers   Perinatal asphyxia,   green fluorescent tubes 30cm above the
 163
 ID:     table   Apgar < 4 at 1 minute and < 6 at  mattress. The baby was placed naked,      Group 2: -154 ± 31 micromol/litre
    5 minutes,   except for eye patches and gonadal
 Evidence level:   Signs of haemolytic disease,   protection, on a Plexiglas surface.
 1 +   secondary hyperbilirubinaemia
        Light spectral range of green tubes was
 Demographics:   350–650 nm and 300–600 for the blue
 Gender (M/F): 13/17   tubes


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