Page 420 - 16Neonatal Jaundice_compressed
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Appendix H: Evidence tables


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                                            Age at entry to study
                                            143.4 ± 48.5 hours
                                            Mean TSB: Not reported
              Author:        Methodology:   N: 50                 Group 1:                                     Mean change in TSB:
              Mohammadzadeh A   RCT                               Supine position                              Group 1: -68 ± 27 micromol/litre
                                            Inclusion:
              Year:          Blinding:      TSB ≥ 256 micromol/litre (49–  Group 2:                            Group 2: -62 ± 21 micromol/litre
              2004           Not reported   72 hours)             Changing position
                                            TSB ≥ 291 micromol/litre
              Country:       Randomisation:   (> 72 hours)        All babies received identical
              Iran           Not reported                         phototherapy for periods of 150 minutes
                                            Exclusion:            followed by 30 minute breaks for
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              ID:            Evidence level:   Haemolytic disease,   feeding and routine nursing care.
                             1 -            Congenital anomalies,   Babies in changing position group were
                                            Cephalhaematoma,      alternated between supine and prone
                                            Metabolic disease
                                                                  Phototherapy discontinued after two
                                            Demographics:         consecutive measurements TSB
                                            Gender (M/F) : Not reported   < 239 micromol/litre
                                            Mean GA: Not reported
                                            Mean BW: Not reported
                                            Age at entry to study
                                            Not reported
                                            Mean TSB:
                                            321 ± 39 micromol/litre
              Author:        Methodology:   N:                    Group 1:                                     Mean duration of phototherapy
              Lau S          RCT            34                    Continuous Phototherapy                      Group 1: 89.9 ± 54.2 hours

              Year:          Blinding:      Inclusion:            Group 2:                                     Group 2: 86.7 ± 28.9 hours
              1984           Not reported   Full-term,            Intermittent Phototherapy – 4 hours on -     Group 3: 100.0 ± 61.0 hours
                                            Birthweight > 2500gms,   4 hours off
              Country:       Randomisation:   TSB between 190 –
              Hong Kong      Not reported   205 micromol/litre    Group 3:
                                                                  Intermittent Phototherapy – 1 hour on -
              ID:            Evidence level:   Exclusion:         3 hours off
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                             1 -            Jaundice with known causes
                                                                  Phototherapy was discontinued when
                                            Demographics:         TSB < 171 micromol/litre
                                            Gender (M/F): Not reported
                                            Mean GA: 39.9 ± 1.5 weeks
                                            Mean BW: 3229 ± 394 gms
                                            Age at entry to study
                                            Not reported
                                            Mean TSB:
                                            198 ± 25 micromol/litre



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