Page 424 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
RCT 38 Eye patches Group 1: 23.9 hours
Year: Group 2: 22.6 hours
1985 Blinding: Inclusion: Group 2:
Not reported Healthy normal labour and Screen
Country: delivery,
Italy Randomisation: Single birth,
Not reported No congenital malformation, Screen consisted of an opaque fabric
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ID: Apgar > 7 at 5 minutes, suspended from the head end of the
Evidence level: Birthweight > 2500 gms, bassinet with ribbons attached to both
1 - Full-term, upper sides of the crib so that the head
Breast –feeding, is covered and the fabric falls freely
No perinatal complications upon the shoulders and neck of the
baby. Two other ribbons tied to the
Exclusion: lower part of the fabric are attached
Babies in Special Care Unit, with adhesive tape behind the neck in a
Haemolytic disease, way that the bay is free to move and the
Hypocalcaemia, fabric does not create any tension in the
Polycythemia neck.

Demographics:
Gender (M/F): 24/14
Mean GA: 39 weeks
Mean BW: 3395 gms
Age at entry to study
66.5 hours
Mean TSB 232 micromol/litre
Author: Methodology: N: Group 1: ET: Max TSB:
Wu P RCT 120 No treatment Group 1: 0/40 Group 1: 161 ± 51 micromol/litre
Group 2: 0/40
Year: Blinding: Inclusion: Group 2: Group 3: 0/40 Group 2: 115 ± 34 micromol/litre
1974 Not reported Preterm babies with birthweight Phototherapy - continuous Group 3: 134 ± 32 micromol/litre
between 1250 and 2000 g Mortality:
Country: Randomisation: Group 3: Group 1: 2/40
USA Randomised cards Exclusion: Phototherapy – Intermittent Group 2: 2/40
Gross congenital anomalies, Group 3: 0/40
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ID: Evidence level: Haemolytic anaemias, Babies in phototherapy group received
1 - Severe respiratory distress 5 days of phototherapy while in
syndrome incubators

Demographics: Phototherapy consisted of 10 20w cool-
Gender (M/F): 59/61 white fluorescent lamps suspended
Mean GA: 34.0 ± 2.5 weeks 45cm above the baby. Average
irradiance during day was
Mean BW: 1736 ± 199 g 0.05microW/cm /nm and at night was
2
Mean age at entry to study: Not 2
reported 0.01microW/cm /nm in the 400 – 500
Mean TSB: Not reported nm wave band.

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