Page 416 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
Mean GA: 39.0 ± 1.03 weeks
Babies were supplemented with 5%
Mean BW: 3395 ± 547 gms glucose (15 mg/kg per day)
Age at entry to study
70.5 ± 23,1 hours Phototherapy discontinued at TSB
Mean TSB: 291± < 200 micromol/litre

35 micromol/litre Rebound jaundice was a rise of
17 micromol/litre after phototherapy
discontinuation
Author: Vecchi C Methodology: N: 84 Group 1: TSB levels – change
RCT Blue Phototherapy 24 hours:
Year: Inclusion: Group 1: -50 ± 23 micromol/litre
1986 Blinding: Hyperbilirubinaemia Group 2:
Not reported Green Phototherapy Group 2: -48 ± 26 micromol/litre
Country: Exclusion:
Italy Randomisation: Blood group incompatibility, Phototherapy units consisted of 8 (blue
Not reported Haemolytic disease, or green) fluorescent tubes positioned
ID: Respiratory distress, 46 cm above the mattress.
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Evidence level: Sepsis The total power irradiance reaching the
1 - baby through two plastic shields was 2.3
2
Demographics: mW/cm for green phototherapy and
Gender (M/F): Not reported 2
Mean GA: 35 weeks 3.2 mW/cm for blue phototherapy
Mean BW: 1930 gms
Age at entry to study Phototherapy was continuous except for
Not reported feeding etc
Mean TSB: Babies were placed in an incubator
227 ± 40 micromol/litre
Author: Sisson T Methodology: N: 72 Group 1: Incomplete data for all Mean duration of phototherapy
RCT Blue Phototherapy outcomes Group 1: 46 ± 15.7 hours
Year: Inclusion:
1972 Blinding: TSB ≥ 150 micromol/litre Group 2: Group 2: 40 ± 18.3 hours
Not reported Special Blue phototherapy Group 3: 75 ± 29.4 hours
Country: Exclusion:
USA Randomisation: Sepsis, Group 3:
Random numbers Respiratory distress, White phototherapy
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ID: Blood group incompatibility,
Evidence level: Haemolytic disease Each phototherapy unit consisted of 10
1 - fluorescent tubes.
Demographics: Irradiance for blue lamps was 0.91
Gender (M/F): Not reported mW/cm 2
Mean GA: Not reported Irradiance for special blue lamps was
Mean BW: 2097 gms 2
Age at entry to study 2.9 mW/cm
Not reported Irradiance for white lamps was 0.32
Mean TSB: 190 micromol/litre mW/cm 2

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