Page 437 - 16Neonatal Jaundice_compressed
P. 437

Appendix H: Evidence tables


 Bibliographic   Study Type &   Number of   Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
 Information   Evidence Level   Patients/Characteristics   (E:C)   (Mean:SD: N)
 Year:   Blinding:   Inclusion:   Group 2:
 1986   Not reported   Preterm babies with gestational  Phototherapy with Chest shields   Late mortality
       age between 26 and 32 weeks      Group 1: 4/38
 Country:   Randomisation:      All babies were receiving early   Group 2: 10/36
 USA   Randomisation chart  Exclusion:   phototherapy to prevent
       None   hyperbilirubinaemia and were nursed
 184
 ID:     Evidence level:      under radiant warmers, receive
 1 +   Demographics:   mechanical ventilation for respiratory
     Gender (M/F):Not reported   distress syndrome.
 Mean GA: 29.4 weeks
 Mean BW: 2034 g   Standard phototherapy units (Air
 Mean age at entry to study: Not  Shields) were used Mean light intensity
 reported   was 4.77 microwatt/cm² per nm
 Mean TSB: micromol/litre
 Chest shields were folded (doubled)
 piece of aluminium foil covered in a
 gauze pad and taped over the left chest.
 Author:   Methodology:   N:   Phototherapy consisted of standard unit     Mean change in Lymphocyte-DNA damage
 Tatli M   Comparative study   47 (14 were healthy controls)   of 4 blue and 2 white fluorescent tubes      PT: 29.1 ± 1.9
    with healthy controls     (Air Shields) with a light range of 480 –
 Year:      Inclusion:   520 nm and an irradiance of   Control: 2.7 ± 2.9
 2008   Blinding:   Term babies with non-  12 microwatt/cm² per nm. Phototherapy
    None   haemolytic hyperbilirubinaemia
 Country:         lasted 72 hours, babies whose TsB
 Turkey   Randomisation:   Exclusion:   declined to normal levels before
    None   None   72 hours were excluded.

 178
 ID:
 Evidence level:   Demographics:
 2 -   Gender (M/F):29/18
     Mean GA: 39.3 ± 0.9 weeks
 Mean BW: 3021 ± 450 g
 Mean age at entry to study:
 113 ± 46 hours
 Mean TSB: Not reported
 Author:   Methodology:   N:      PT   No increased risk of developing childhood malignant melanoma
 Berg P   Retrospective   150      Cases: 0/30   in skin of babies who received phototherapy
    matched case–control     Controls: 11/120
 Year:   study   Inclusion:
 1997      30 cases of childhood cancer
    Blinding:   before 20 years of age and 120
 Country:   None   controls
 Sweden
    Randomisation:   Exclusion:
 180
 ID:     None   None

 Evidence level:   Demographics:


                                                                 291
   432   433   434   435   436   437   438   439   440   441   442