Page 440 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)

Country: Randomisation:
USA Not reported

177
ID: Evidence level:
1 -

Author: Methodology: N: Phototherapy consisted of Heart Rate variability – SD1
Weissman A Before–after study 30 an overhead LED unit (neoBLUE) Before: 12 ± 8 ms
Irradiance was 34 microwatt/cm² per
Year: Blinding: Inclusion: nm. After : 8 ± 4ms
2009 None Jaundice P < 0.02
GA = 37 – 42 weeks
Country: Randomisation: Apgar (1 min) > 7 Heart Rate variability – SD2
Israel None Apgar (5 min) > 8 Before: 33 ± 16 ms

189
ID: Evidence level: Exclusion: After : 22 ± 10 ms
3 Haemolysis, P < 0.01
G6PD,
Fever, Heart Rate variability – SDDN
Maternal use of narcotic Before: 30 ± 14 ms
analgesic drugs during labour,
Ruptured membranes > 18ours After : 18 ± 7 ms
P < 0.01
Demographics:
Gender (M/F)16/14 Heart Rate variability – RMSSD
Mean GA: 39.1 ± 1.5 weeks Before: 18 ± 12 ms
Mean BW: 3116 ± 392 g After : 11 ± 6 ms
Mean age at entry to study: P < 0.02
53 ± 31 hours
Mean TSB:
238 ± 43 micromol/litre
Author: Methodology: N: Collected information included, Received There was no difference in nevus counts as a function of
Mahe E RCT 828 Phototype (Fitzpatrick’s classification), phototherapy = 180 exposure to neonatal phototherapy.
Behaviour in the sun,
Year: Blinding: Inclusion: Sun protection policy, Controls = 648 Mean melanocytic count:
2009 Not reported Primary school children (age 8 – History of phototherapy for neonatal Phototherapy 16.8 ± 9.8
9) jaundice
Country: Randomisation: Controls:16.7 ± 10.5
France Not reported Exclusion: A melanocytic nevus count was
Not reported conducted by trained nurses who was
181
ID: Evidence level: blind to whether the child had received
1+ Demographics: phototherapy
Gender (M/F) 415/413
Mean GA: N/A The size of exposed body parts (arm and

293