Page 443 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
Mean BW: NA back)was record < 2mm, 2–5mm,
Mean age at entry to study: N/A > 5mm
Mean TSB: N/A
Author: Methodology: N: Group 1: Intensive phototherapy Mean duration of phototherapy:
Ayclcek A Case control study 65 Group 1: 54 ± 6 hours
Group 2: Conventional phototherapy
Year: Blinding: Inclusion: Group 2: 61 ± 10 hours
2008 Not reported Indirect hyperbilirubinaemia Group 3: No phototherapy Group 3: N/A
TSB > 222 micromol/litre
Country: Randomisation: Phototherapy consisted of six white
Turkey Not reported Exclusion: fluorescent tubes 40cm above the baby. DNA damage (arbitrary units):
Severe congenital malformation, 12–16 microwatt/cm² per nm. Group 1: 32 ± 9
179
ID: Evidence level: Preterm birth or postmaturity,
2 - Maternal diabetes, Group 2: 28 ± 9
Birth asphyxia, Intensive phototehrpay consisted of 12 Group 3: 21 ± 10
Sepsis, white fluorescent tubes 20cm above and P < 0.001
Haemolysis due to ABO/Rh below the baby.
incompatibility, 30–34 microwatt/cm² per nm.
Phototherapy before blood was
collected, DNA damage was measured in blood
Bilirubin rising by more than samples taken after phototherapy. The
85 micromol./litre day in first images of 100 randomly selected nuclei
24 hour, (50 from each of two replicate slides)
Tsb > 410 micromol/litre were analysed visually.

Demographics:
Gender (M/F) 35/28
Mean GA: Not reported
Mean BW: Not reported
Mean age at entry to study: Not
reported
Mean TSB: Not reported

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