Page 528 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C4.3. Comparison between watchful waiting and radiation therapy (continued)
Author, Year Study name Comparison Outcome Followup Sample size Results Factors included in the
[Pubmed ID] /Database definition/ (yr) per group model
measurement
Study design instrument
Thong 224 Eindhoven RT vs. “AS” General QoL: Mean 8 yr RT: 71 RT was negatively associated Matching: cancer stage,
2009 Cancer SF-36 scores AS: 71 with physical functioning and tumor
19747357 Registry bodily pain dimensions of the grade, age at diagnosis (
(ECR) Expanded SF-36, spiritual and total ±2 yrs), and number of
Retrospective Prostate wellbeing scores of the QoL- years since diagnosis (±2
matched cohort Cancer Index CS, and bowel function and yrs).
(EPIC): bowel bother of EPIC index.
urinary and Multivariate model adjusted
bowel No other significant for comorbidity and disease
functioning, associations between general progression
and urinary QoL, cancer-specific QoL, or
and bowel disease-specific QoL scores
bother and management strategy (RT
vs. “AS”).
Quality of Life
– Cancer
Survivors
(QOL-CS)

C-182