Page 532 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C4.3. Comparison between watchful waiting and radiation therapy (continued)
Author, Year Study name Comparison Outcome Followup Sample size Results Factors included in the
[Pubmed ID] /Database definition/ (yr) per group model
measurement
Study design instrument
Observation HRQoL 1 yr post- Observation: Estimates are means (SE) Treatment group interaction
vs. RT questionnaire treatment 87 based on linear mixed model for with time, age, time of
composed of regression RT: 75 Observation vs. RT: treatment.
items from the estimates Physical functioning, 72.7 (2.5);
RAND-36 item 76.7 (2.5) P values for comparisons
Health Role-physical, 60.2 (4.3); 66.3 between treatment groups
Survey. All (4.2) NR.
scales were Role-emotional, 80.0 (3.8); 81.9
scored 0 to (3.7)
100; optimal Emotional well-being, 76.2
health or (1.6); 74.6 (1.6)
functioning = Bodily pain, 75.9 (2.4); 75.6
100. (2.3)
Social functioning, 80.4 (2.5);
84.6 (2.4)
Energy/fatigue, 56.1 (2.1); 56.7
(2.1)
General health perception, 60.2
(2.3); 62.1 (2.3)
Health change, 54.3 (2.6); 61.0
(2.5)
Health distress, 81.6 (2.0); 81.8
(2.0)
Self-esteem, 78.2 (1.9); 79.8
(1.8)

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