Page 527 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C4.3. Comparison between watchful waiting and radiation therapy (continued)
Author, Year Study name Comparison Outcome Followup Sample size Results Factors included in the
[Pubmed ID] /Database definition/ (yr) per group model
measurement
Study design instrument
would you feel if you lived the
rest of your life with your sexual
problems as they are now?”
(P=0.819).
Litwin 229 CaPSURE WW vs. RT Mean SF-36 1.5 yr RT: 104 WW: Mental domain: 75 ± 1.9 vs. 81 Comorbidity count, PSA at
2002 scores at 24 66 ± 2.4 diagnosis, Gleason score
12115317 months Role of limitations due to on biopsy, age at the end of
emotional problems domain: 81 treatment
Retrospective ± 3.8 vs. 86 ± 4.7
cohort Vitality domain: 61 ± 2.5 vs. 66
± 3.1
Social function domain: 86 ± 2.7
vs. 89 ± 2.2 (P < 0.05)
Schapira 226 4 RT vs. EM Disease- 1 yr RT: 40 No significant difference Patient age, comorbidity,
2001 academically specific QoL: EM: 25 between RT and EM groups in TNM, PSA, race, marital
11242319 affiliated UCLA any domain in both disease- status, working status, and
Wisconsin Prostate specific and general QoL years of education.
Prospective hospitals, cancer Index measures.
cohort including 2
VA Medical General QoL:
Centers SF-36 scores

C-181