Page 524 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
P. 524

Appendix Table C4.3. Comparison between watchful waiting and radiation therapy (continued)
                                        Author, Year       Study name      Comparison  Outcome               Followup      Sample size        Results                             Factors included in the
                                        [Pubmed ID]        /Database                       definition/       (yr)          per group                                              model
                                                                                           measurement
                                        Study design                                       instrument
                                                                                                                                              Stool frequency: 1.5 vs. 2.0
                                                                                                                                              (P=0.296)
                                                                                                                                              Blood in stools: 0.4 vs. 1.4
                                                                                                                                              (P=0.085)
                                                                                                                                              Stool leakage: 1.0 vs. 1.2
                                                                                                                                              (P=0.430)
                                                                                                                                              Bowel movements: 2.4 vs. 2.1
                                                                                                                                              (P=0.660)
                                                                                                                                              Cramp: 0.0 vs. 0.1 (P=0.295)
                                                                                                                                              Planning: 1.0 vs. 1.5 (P=0.765)
                                                                                                                                              Mucus: 0.5 vs. 0.9 (P=0.103)
                                                                                                                                              Sexual bother: 3.8 vs. 7.4
                                                                                                                                              (P=0.011)
                                                                                                                                              Desire: 6.4 vs. 8.0 (P=0.169)
                                                                                                                                              Erection: 7.2 vs. 8.4 (P=0.292)

                                                                                                                                              Weak urinary stream: 3.0 vs.
                                                                                                                                              4.8 (P=0.034)

                                                                                                                                              No difference was observed at
                                                                                                                                              10 years between RT and WW
                                                                                                                                              regarding the question “How
                                                                                                                                              would you feel if you lived the
                                                                                                                                              rest of your life with your urinary
                                                                                                                                              problems as they are now?”
                                                                                                                                              (P=0.643).

                                                                                                                                              No difference was observed at
                                                                                                                                              10 years between RT and WW
                                                                                                                                              regarding the question “How
                                                                                                                                              would you feel if you lived the
                                                                                                                                              rest of your life with your bowel
                                                                                                                                              problems as they are now?”
                                                                                                                                              (P=0.653).

                                                                                                                                              No difference was observed at
                                                                                                                                              10 years between RT and WW
                                                                                                                                              regarding the question “How





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