Page 526 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
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Appendix Table C4.3. Comparison between watchful waiting and radiation therapy (continued)
                                        Author, Year       Study name      Comparison  Outcome               Followup      Sample size        Results                             Factors included in the
                                        [Pubmed ID]        /Database                       definition/       (yr)          per group                                              model
                                                                                           measurement
                                        Study design                                       instrument
                                                                                                                                              would you feel if you lived the
                                                                                                                                              rest of your life with your sexual
                                                                                                                                              problems as they are now?”
                                                                                                                                              (P=0.819).
                                        Litwin 229         CaPSURE         WW vs. RT       Mean SF-36        1.5 yr        RT: 104 WW:        Mental domain: 75 ± 1.9 vs. 81      Comorbidity count, PSA at
                                        2002                                               scores at 24                    66                 ± 2.4                               diagnosis, Gleason score
                                        12115317                                           months                                             Role of limitations due to          on biopsy, age at the end of
                                                                                                                                              emotional problems domain: 81       treatment
                                        Retrospective                                                                                         ± 3.8 vs. 86 ± 4.7
                                        cohort                                                                                                Vitality domain: 61 ± 2.5 vs. 66
                                                                                                                                              ± 3.1
                                                                                                                                              Social function domain: 86 ± 2.7
                                                                                                                                              vs. 89 ± 2.2 (P < 0.05)
                                        Schapira 226       4               RT vs. EM       Disease-          1 yr          RT: 40             No significant difference           Patient age, comorbidity,
                                        2001               academically                    specific QoL:                   EM: 25             between RT and EM groups in         TNM, PSA, race, marital
                                        11242319           affiliated                      UCLA                                               any domain in both disease-         status, working status, and
                                                           Wisconsin                       Prostate                                           specific and general QoL            years of education.
                                        Prospective        hospitals,                      cancer Index                                       measures.
                                        cohort             including 2
                                                           VA Medical                      General QoL:
                                                           Centers                         SF-36 scores

































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