Page 531 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C4.3. Comparison between watchful waiting and radiation therapy (continued)
Author, Year Study name Comparison Outcome Followup Sample size Results Factors included in the
[Pubmed ID] /Database definition/ (yr) per group model
measurement
Study design instrument
Lubeck 227 CaPSURE Observation HRQoL Immediate Observation: Estimates are means (SE) Treatment group interaction
1999 vs. RT questionnaire post- 87 based on linear mixed model for with time, age, time of
9886609 composed of treatment RT: 75 Observation vs. RT: treatment.
items from the period Physical functioning, 74.9 (2.6);
Prospective RAND-36 item regression 76.5 (3.0) P values for comparisons
cohort Health estimates Role-physical, 61.7 (4.5); 51.0 between treatment groups
Survey. All (5.1) NR.
scales were Role-emotional, 72.6 (3.9); 65.8
scored 0 to (4.5)
100; optimal Emotional well-being, 76.4
health or (1.7); 77.5 (1.9)
functioning = Bodily pain, 73.4 (2.4); 76.4
100. (2.7)
Social functioning, 80.9 (2.5);
76.0 (2.8)
Energy/fatigue, 61.5 (2.2); 58.1
(2.5)
General health perception, 60.4
(2.3); 65.3 (2.7)
Health change, 38.1 (2.7); 38.1
(3.0)
Health distress, 77.3 (2.1); 80.4
(2.3)
Self-esteem, 82.1 (1.9); 83.3
(2.2)

C-183