Page 479 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes Comments
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
1992 Not reported Babies with Rh antigens born Phototherapy + IVIG 500 mg/kg body No adverse effects were protocol violations
to mothers lacking Rh weight over 2 hours noted
Country: Randomisation: antigens,
Germany Not reported Positive Coombs’ test

207
ID: Evidence level: Exclusion:
1 - Not reported

Demographics:
Gender (M/F): Not reported
Mean GA: Not reported
Mean BW: Not reported
Age at entry to study: Not
reported
Mean TSB: Not reported
Author: Methodology: N: Group 1: Exchange transfusion: Max TSB:
Dagoglu T RCT 41 Phototherapy Group 1: 15/19 Group 1: 224 ± 99 micromol/litre
Group 2: 4/22
Year: Blinding: Inclusion: Group 2: Group 2: 198 ± 106 micromol/litre
1995 None Babies with Rh antigens born Phototherapy + IVIG 500 mg/kg body
to mothers lacking Rh weight as soon as possible after birth
Country: Randomisation: antigens,
Turkey Random numbers Positive Coombs’ test
table with sealed
208
ID: envelopes Exclusion:
Not reported
Evidence level:
1 ++ Demographics:
Gender (M/F): 25/16
Mean GA: 36.1 ± 2.0 weeks
Mean BW: 2776 ± 419 g
Age at entry to study: Not
reported
Mean TSB: Not reported
Author: Methodology: N: Group 1: Exchange transfusion: Mean duration of treatment:
Nasseri F RCT 34 Phototherapy Group 1: 11/17 Group 1: 154 ± 48 hours
Group 2: 3/17
Year: Blinding: Inclusion: Group 2: Group 2: 119 ± 23 hours
2006 Not reported Gestation age > 37 weeks, Phototherapy + IVIG No adverse effects were
Positive Coombs’ test, noted
Country: Randomisation: Significant IVIG (500 mg/kg body weight) was given
Iran Not reported hyperbilirubinaemia rising at with 2–4 hours of admission for 3
8.5micromol/litre per hour, consecutive doses each 12 hours
209
ID: Evidence level: TsB below exchange
1 - transfusion levels,

Exclusion:

312