Page 482 - 16Neonatal Jaundice_compressed
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Neonatal jaundice


              Bibliographic   Study Type &   Number of          Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes      Comments
              Information    Evidence Level   Patients/Characteristics                      (E:C)             (Mean:SD: N)
                                            Term babies
                                            Gender (M/F): 6/14
                                            Mean GA: 39.1 ± 0.3 weeks
                                            Mean BW: 3286 ± 39 g
                                            Age at entry to study:
                                            90 ± 1.5 hours
                                            Mean TSB:
                                            298 ± 5 micromol/litre

                                            Preterm babies
                                            Gender (M/F): 9/11
                                            Mean GA: 33.4 ± 0.3 weeks
                                            Mean BW: 2077 ± 88 g
                                            Age at entry to study:
                                            76 ± 2.9 hours
                                            Mean
                                            TSB:198 ± 5micromol/litre
              Author:        Methodology:   N:                  Group 1:                                      Mean decrease in TSB:
              Tan K          CCT            84                  Phototherapy                                  Group 1: -168 ± 24 micromol/litre

              Year:          Blinding:      Inclusion:          Group 2:                                      Group 2: -150 ± 20 micromol/litre
              1984           Not reported   Term babies with non-  Phototherapy + Cholestyramine
                                            haemolytic
              Country:       Randomisation:   hyperbilirubinaemia (TsB   Babies received 1.5 g/kg per day of
              Singapore      Alternation    ≥ 256.5micromol/litre)   cholestyramine powder mixed in milk
                                            Normal G6PD status,
                221
              ID:            Evidence level:   No isoimmunisation,
                             2 -            no cephalhaematoma

                                            Exclusion:
                                            Not reported

                                            Demographics:
                                            Gender (M/F): Not reported
                                            Mean GA: 38.9 ± 0.2 weeks
                                            Mean BW: 3154 ± 139 g
                                            Age at entry to study:
                                            84 ± 2.9 hours
                                            Mean TSB:
                                            298 ± 5micromol/litre
              Author: Martin J   Methodology:   N: 100          Group 1:                    ET:               Mean duration of phototherapy   No significant
                             CCT                                Usual nursery care          Group 1: 3/35     Group 1: NA                   differences


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