Page 481 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes Comments
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
Risk factors for
hyperbilirubinaemia, i.e.
sepsis, G6PD deficiency

Demographics:
Gender (M/F): 14/20
Mean GA: Not reported
Mean BW: 2683 ± 292 g
Age at entry to study:
20.2 ± 9.5 hours
Mean TSB:
254 ± 57micromol/litre
Author: Methodology: N: Group 1: No adverse effects were Mean decrease in TsB:
Farhat A RCT 104 Phototherapy + Placebo noted Group 1: -164
Group 2: -154
Year: Blinding: Inclusion: Group 2:
2006 Double-blind TsB between 308 and Phototherapy + Shirkhest
496micromol/litre
Country: Randomisation: Shirkhest (6 g) was diluted in 8mL of
Iran Not reported Exclusion: distilled water while the control group
Birthweight < 2500 g, were given a starch solution (0.1%, 8mL)
225
ID: Evidence level: Renal failure, coloured with 1 drop of caramel solution
1 - Systemic infections, to appear identical to Shirkhest solution.
Already taken Shirkhest
Phototherapy was discontinued at
Demographics: 256micromol/litre
Gender (M/F): Not reported
Mean GA: Not reported
Mean BW: Not reported
Age at entry to study: Not
reported
Mean TSB:
401 ± 53 micromol/litre
Author: Methodology: N: Group 1: No adverse effects were Mean duration of treatment:
Nicolopoulos D CCT 40 Phototherapy noted Term babies
Group 1: 84.4 ± 12 hours
Year: Blinding: Inclusion: Group 2:
1978 Not reported Jaundice Phototherapy + Cholestyramine Group 2: 41.8 ± 5.5 hours

Country: Randomisation: Exclusion: Babies received 1.5 g/kg per day of Preterm babies
Greece Alternation Babies of diabetic mothers, cholestyramine powder mixed in milk Group 1: 73.3 ± 9 hours
Rh incompatibility,
220
ID: Evidence level: Perinatal asphyxia, No Phenobarbital, other medications, or Group 2: 47.0 ± 6 hours
2 - Large cephalhaematoma parenteral fluids were administered.

Demographics:

313