Page 400 - 16Neonatal Jaundice_compressed
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Appendix H: Evidence tables


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                                                                  at maximal power. Irradiance was an
                                                                                    2
                                                                  average of 19.01 microW/cm /nm when
                                                                  measured at the centre and at the four
                                                                  corners.

                                                                  The standard fiberoptic phototherapy
                                                                  consisted of a pad, 11 X 24 cm
                                                                  (illuminated part was 11 X 16cm) which
                                                                  was used without its sheath and at
                                                                  maximal power. The irradiance was
                                                                  calculated to be 23% more than that of
                                                                  the standard fiberoptic pad.

                                                                  The double fiberoptic phototherapy
                                                                  consisted of two standard pads one on
                                                                  the back and one the front of the baby.

                                                                  Phototherapy was terminated when TSB
                                                                  < 188 micromol/litre on at least two
                                                                  occasions

                                                                  Phototherapy was deemed to have failed
                                                                  when TSB values exceeded start level
                                                                  on at least two occasions and when
                                                                  direct bilirubin was minimal < 0.6
                                                                  MG/DL
              Author: Van Kamm A  Methodology:   N: 124           Group 1:                   ET:               Mean duration of phototherapy
                             RCT                                  Conventional phototherapy   Group 1: 3/68    Group 1: Not reported
              Year:                         Inclusion:                                       Group 2: 4/56     Group 2: Not reported:
              1998           Blinding:      Preterm babies with birthweight  Group 2:
                             Not reported   < 2000gms,            Fiberoptic phototherapy    Treatment failure:   Mean change in TSB:
              Country:                      Nonhaemolytic jaundice                           Group 1: 27/68    Group 1: -2 ± 25 micromol/litre
              Netherlands    Randomisation:                       Conventional phototherapy consisted of  Group 2: 29/56
                             Not reported but   Exclusion:        4 overhead fluorescent lamps arranged        Group 2: -2 ± 20 micromol/litre
                154
              ID:            sealed envelopes used  Prior phototherapy,   in an arc 40 cm above the baby. Baby
                                            Met criteria for exchange   was naked except for eye patches. The
                             Evidence level:   transfusion        light range is in the 380 – 480 nm range.    :
                             1 +                                  Irradiance level was
                                                                           2
                                            Demographics:         16 microW/cm /nm
                                            Gender (M/F) : 72/52
                                            Mean GA: 29.7 ± 2.4 weeks   Fiberoptic phototherapy (Ohmeda
                                            Mean BW: 1250 ± 353 gms   BiliBlanket) consisted of a halogen
                                                                  lamp illuminating a flat mat using a
                                            Age at entry to study   fiberoptic attachment containing 2400
                                            26.5 ± 17.5           optic givers woven into the mat. Baby
                                            Mean TSB:             was naked.
                                            94 ± 36 micromol/litre   The illuminating part of the mat is 11 X


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