Page 401 - 16Neonatal Jaundice_compressed
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Appendix H: Evidence tables


 Bibliographic   Study Type &   Number of   Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
 Information   Evidence Level   Patients/Characteristics   (E:C)   (Mean:SD: N)
 at maximal power. Irradiance was an
 2
 average of 19.01 microW/cm /nm when
 measured at the centre and at the four
 corners.

 The standard fiberoptic phototherapy
 consisted of a pad, 11 X 24 cm
 (illuminated part was 11 X 16cm) which
 was used without its sheath and at
 maximal power. The irradiance was
 calculated to be 23% more than that of
 the standard fiberoptic pad.

 The double fiberoptic phototherapy
 consisted of two standard pads one on
 the back and one the front of the baby.

 Phototherapy was terminated when TSB
 < 188 micromol/litre on at least two
 occasions

 Phototherapy was deemed to have failed
 when TSB values exceeded start level
 on at least two occasions and when
 direct bilirubin was minimal < 0.6
 MG/DL
 Author: Van Kamm A  Methodology:   N: 124   Group 1:   ET:   Mean duration of phototherapy
    RCT      Conventional phototherapy   Group 1: 3/68   Group 1: Not reported
 Year:      Inclusion:      Group 2: 4/56   Group 2: Not reported:
 1998   Blinding:   Preterm babies with birthweight  Group 2:
    Not reported   < 2000gms,   Fiberoptic phototherapy   Treatment failure:   Mean change in TSB:
 Country:      Nonhaemolytic jaundice      Group 1: 27/68   Group 1: -2 ± 25 micromol/litre
 Netherlands   Randomisation:      Conventional phototherapy consisted of  Group 2: 29/56
    Not reported but   Exclusion:   4 overhead fluorescent lamps arranged      Group 2: -2 ± 20 micromol/litre
 154
 ID:     sealed envelopes used  Prior phototherapy,   in an arc 40 cm above the baby. Baby
    Met criteria for exchange   was naked except for eye patches. The
 Evidence level:   transfusion   light range is in the 380 – 480 nm range.   :
 1 +      Irradiance level was
 2
     Demographics:   16 microW/cm /nm
 Gender (M/F) : 72/52
 Mean GA: 29.7 ± 2.4 weeks   Fiberoptic phototherapy (Ohmeda
 Mean BW: 1250 ± 353 gms   BiliBlanket) consisted of a halogen
 lamp illuminating a flat mat using a
 Age at entry to study   fiberoptic attachment containing 2400
 26.5 ± 17.5   optic givers woven into the mat. Baby
 Mean TSB:   was naked.
 94 ± 36 micromol/litre   The illuminating part of the mat is 11 X


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