Page 397 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
RCT Conventional Phototherapy Group 1: 0/21 Group 1: Not reported
Year: Inclusion: Group 2: 0/20 Group 2: Not reported
2002 Blinding: Group 2:
Not reported Exclusion: Fiberoptic Phototherapy
Country: Mean change in TSB:
Italy Randomisation: Demographics: Conventional phototherapy ( ‘Photo- Group 1: -55 ± 16 micromol/litre
Not report but sealed Gender (M/F) : Not reported Therapie 800’) consisted of a unit
142
ID: envelopes used Mean GA: 39.6 ± 1.2 weeks incorporating a metal vapour discharge Group 2: -51 ± 23 micromol/litre
blue lamp with 2 filters (an infrared
Evidence level: Mean BW: 3236 ± 425 gms filter and a Plexiglas ultraviolet filter).
1 + Age at entry to study A fan was fitted to remove heat
Not reported generated by lamp.
Mean TSB:
296 ± 32 micromol/litre Fiberoptic phototherapy (BiliBlanket
PT) consisted of a 140W quartz halogen
lamp with a built-in dichroic reflector
with low infrared and ultraviolet
radiation reflectivity. Light range was
restricted to 400 – 550 nm.

All babies were naked in a supine
position at a stabilised room
temperature.
Author: Methodology: N: 136 Group 1: ET: Mean duration of phototherapy
Romagnoli C RCT Conventional phototherapy Group 1: 2/33 Group 1: 90.2 ± 24.3 hours
Inclusion: Group 2: 2/35
Year: Blinding: TSB> 103 micromol/litre Group 2: Group 3: 1/35 Group 2: 92.1 ± 43.3 hours
2006 No reported GA < 30 weeks Fiberoptic (Wallaby) phototherapy Group 4: 0/33 Group 3: 94.4 ± 43.3 hours
Exclusion:
Country: Randomisation: Not reported Group 3: Erythema: Group 4: 75.1 ± 23.6 hours
Italy Not reported but Fiberoptic (BiliBlanket) phototherapy Group 1: 10/33
sealed envelopes used Demographics: Group 2: 9/35
152
ID: Gender (M/F): 72/64 Group 4: Group 3: 8/35 Max TSB::
Evidence level: Mean GA: 27.9 ± 1.4 weeks Combined conventional and Fiberoptic Group 4: 12/33 Group 1: 157 ± 43 micromol/litre
1 + (Wallaby) phototherapy
Mean BW: 1019 ± 283 gms Treatment failure: Group 2: 169 ± 56 micromol/litre
Age at entry to study Conventional phototherapy consisted of Group 1: 2/33 Group 3: 161 ± 44 micromol/litre
38.3 ± 7.1 hours standard phototherapy composed of 4 Group 2: 4/35 Group 4: 130 ± 22 micromol/litre
Mean TSB: 109 fluorescent lamps and 4 blue lamps Group 3: 1/35
Group 4: 0/33
40cm above the baby.
± 5 micromol/litre Irradiance at skin level was
2
22 – 24 microW/cm /nm. Babies were
naked except for eye patches and
disposable diapers. Baby position was
changed from prone to supine and vice
versa every 6 hours.

Fiberoptic Wallaby phototherapy

271