Page 392 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
63.2 ± 15.0 hours relative humidity of 60%.
Mean TSB:
241 ± 9 micromol/litre
Author: Al-Alaiyan S Methodology: N: 46 Group 1: ET: Mean duration of phototherapy
RCT Conventional phototherapy Group 1: 0/15 Group 1: 52.8 ± 24.8 hours
Year: Inclusion: Group 2: 0/16
1996 Blinding: GA > 36 weeks, Group 2: Group 3: 0/15 Group 2: 47.5 ± 24.8 hours
Not reported Nonhemolytic jaundice Fiberoptic phototherapy Group 3: 50.7 ± 24.8 hours
Country: Age > 1 day, Rebound jaundice:
Saudi Arabia Randomisation: Normal hemoglobin, Group 3: Group 1: 0/15 Mean change in TSB:
Allocation method No evidence of blood group Combined phototherapy and fiberoptic Group 2: 0/16
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ID: not reported but incompatibility, phototherapy Group 3: 0/15 Group 1: -14 ± 28 micromol/litre
shuffled, sealed Group 2: 19 ± 35 micromol/litre
envelopes used Exclusion: Conventional Phototherapy (Air Shields
Not reported Fluoro-Lite) consisted of a standard unit Group 3: -23 ± 39 micromol/litre
Evidence level: of blue and white fluorescent bulbs 50 :
1 - Demographics: cm from the baby.
Gender (M/F): 23/23 Mean irradiance was
2
Mean GA: 37.9 ± 2.08 weeks 11.6 ± 2.2microW/cm /nm
Mean BW: 2921 ± 696 gms Light range = 425 – 475 nm
Age at entry to study Phototherapy was interrupted for
feeding etc for an average of 115
37.9 ± 24.1 hours minutes per day.
Mean TSB: Babies were naked except for eye
185 ± 56 micromol/litre patches.

Fiberoptic phototherapy (BiliBlanket)
consisted of a halogen lamp linked to a
fiberoptic blanket.
Mean irradiance was
2
22.3 ± 2.2microW/cm /nm
Light range = 400 – 500 nm
Fiberoptic phototherapy was
continuous.

Combined therapy consisted of both
conventional and fiberoptic
phototherapy as above.
Author: Pezzati M Methodology: N: 39 Group 1: ET:
RCT Conventional phototherapy Group 1: 0/19
Year: Inclusion: Group 2: 0/20
2000 Blinding: Preterm babies with Group 2:
Clinician blinded hyperbilirubinaemia Fiberoptic phototherapy
Country: > 171 micromol/litre
Italy Randomisation:
Allocation method Exclusion: Conventional Phototherapy (Photo grph

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