Page 390 - 16Neonatal Jaundice_compressed
P. 390

Neonatal jaundice


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                             Evidence level:   they reached 200 micromol/litre  blue lamps) positioned above the baby.
                             1 -                                  Babies were naked, with eyes covered,
                                            Exclusion:            and were alternate between prone and
                                            Evidence of hemolysis   supine position every 6 hours.
                                                                  Irradiance at blanket level was
                                            Demographics:         7.0 ± 0.5microW/cm /nm.
                                                                                2
                                            Gender (M/F): Not reported
                                            Mean GA: 39.6 ± 1.6 weeks
                                            Mean BW: 3197 ± 475   Fiberoptic phototherapy (Wallaby
                                                                  Phototherapy System) consisted of a
                                            Age at entry to study
                                            Not reported          single fiberoptic pad linked to a lightbox
                                            Mean TSB:             with 150-watt halogen lamp and a fan
                                                                         2
                                            186 ± 86 micromol/litre   with 150.ft /minute air volume.
                                                                  Irradiance spectrum was between 425
                                                                  and 475 nm.
                                                                  Irradiance at blanket level was
                                                                                2
                                                                  7.0 ± 0.5microW/cm /nm.
                                                                  Babies were placed naked on the
                                                                  blanked. While nursing the mother
                                                                  could hold the baby wrapped in the
                                                                  blanket

                                                                  In both group babies were kept on
                                                                  phototherapy for 48 hours but could be
                                                                  withdrawn at any stage.
              Author:        Methodology:   N: 23                 Group 1:                   ET:               Mean duration of phototherapy
              Dani C         RCT                                  Conventional phototherapy   Group 1: 0/12    Group 1: 43.0 ± 3.1 hours
                                            Inclusion:                                       Group 2: 0/11
              Year:          Blinding:      Preterm (GA < 34 weeks),   Group 2:                                Group 2: 38.7 ± 4.5 hours
              2004           Not reported   No haemolytic jaundice, not on  Fiberoptic phototherapy
                                            respiratory support,                                               Mean change in TSB:
              Country:       Randomisation:   Clinically stable.   Conventional Phototherapy consisted of      Group 1: -69 ± 13 micromol/litre
              Italy          Allocation method                    a Photo-Therapie 800 system. Baby was
                             not reported but   Exclusion:        naked except for eye patches and in a        Group 2: -62 ± 17 micromol/litre
              ID:            sealed envelopes used  Major congenital   supine position.
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                                            malformations, patent ductus   Irradiance and light range not reported
                             Evidence level:   arteriosus, intracranial
                             1 -            haemorrhage,          Fiberoptic phototherapy (BiliBlanket)
                                            Perinatal asphyxia, receiving   consisted of a mat that covered the baby
                                            cardiovascular drugs   up to the upper abdomen.
                                                                  Irradiance and light range not reported
                                            Demographics:
                                            Gender (M/F): Not reported   To avoid trans-epidermal water loss the
                                            Mean GA: 31.0 ± 1.8 weeks   babies were placed in incubators with a
                                                                  thermo-monitoring system to maintain
                                            Mean BW: 1468 ± 400 gms   normal body temperature (46.5 C) at a
                                                                                      o
                                            Age at entry to study

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