Page 386 - 16Neonatal Jaundice_compressed
P. 386

Neonatal jaundice


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                                            72 hours              lights 38 cm above the baby.                 Group 2: - 156 ± 67 micromol/litre
                             Evidence level:   TSB ≥ 291 micromol/litre at
                             1 -            ≥ 72 hours            Double Conventional phototherapy             Stools/day:
                                                                  consisted of single phototherapy plus an
                                            Exclusion:            additional bank of 8 20watt daylight         Group 1: 2.8 ± 1.7
                                            Babies who had been on   fluorescents lamps 32 cm below the        Group 2: 2.2 ± 1.4
                                            ventilator support or incubator,  baby.
                                            Babies who had been on   A ventilated fan was used to prevent
                                            phototherapy,         overheating
                                            Direct hyperbilirubinaemia
                                                                  Target irradiance was 9–
                                            Demographics:         10microW/cm /nm
                                                                           2
                                            Gender (M/F) : 34/17
                                            Mean GA: 38.7 ± 1.29 weeks   Phototherapy was discontinued when
                                            Mean BW: 3104 ± 284   TSB < 205 micromol/litre at < 96 hours
                                                                  of age or TSB < 256 micromol/litre at
                                            Age at entry to study   > 96 hours of age
                                            74.6 ± 27.4
                                            Mean TSB:
                                            316 ± 47 micromol/litre
              Author:        Methodology:   n: 60                 Group 1:                   ET:               Mean change in TSB:
              Boonyarittipong P   RCT                             Single Conventional phototherapy   Group 1: 0/30   Group 1: -111 ± 39 micromol/litre
                                            Inclusion:                                       Group 2: 0/30
              Year: 2008     Blinding:      Full term (37–        Group 2:                                     Group 2: -144 ± 36 micromol/litre
                             Not reported   42 weeks),            Double Conventional phototherapy   Treatment failure:
              Country: Thailand             Birthweight > 2500gms,                           Group 1: 0/30     Stools/day:
                             Randomisation:   Apgar > 6 T 1 and 5 minutes                    Group 2: 0/30     Group 1: 2.8 ± 1.7
                137
              ID:            Not reported   TSB between 222 -     Single Conventional phototherapy
                                            340 micromol/litre,   consisted of 4 blue and 2 daylight           Group 2: 2.2 ± 1.4
                             Evidence level:   Nonhemolytic       fluorescent lamps at least 30 cm above
                             1 -            hyperbilirubinaemia   the baby
                                            Exclusively breastfed,   Mean irradiance was
                                                                                 2
                                                                  32.7 ± 2.6microW/cm /nm
                                            Exclusion:
                                            Not reported            Baby wore eye patches and cotton

                                            Demographics:         diapers
                                            Gender (M/F): 32/28     Double Conventional phototherapy
                                            Mean GA: 38.6 ± 1.15 weeks   (Neonatal Jaundice phototherapy
                                            Mean BW: 3130 ± 311 gms   apparatus/XHZ) was single
                                                                  phototherapy and an additional bank of
                                            Age at entry to study
                                            Not reported          4 blue fluorescent lamps 25 cm beneath
                                            Mean TSB:             the bassinet.
                                                                  A fan was used to prevent overheating
                                            260 ± 30 micromol/litre
                                                                  Mean irradiance of overhead unit was


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