Page 382 - 16Neonatal Jaundice_compressed
P. 382

Neonatal jaundice


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
              Author: Ju S   Methodology:   n: 29                 Group 1:                   ET:
                             RCT                                  No treatment               Group 1: 0/13
              Year: 1991                    Inclusion: TSB between 205 and                   Group 2: 0/13
                             Blinding:      256 micromol/litre    Group 2:
              Country: Taiwan   Not reported   Full term singletons   Conventional phototherapy   Treatment failure:
                                            Normal pregnancy      :                          Group 1: 4/17
                134
              ID:            Randomisation:   Normal birth/caesarean                         Group 2: 0/13
                                                           th
                             Not reported   Birthweight between 10  and   Conventional Phototherapy consisted of
                                             th                   a portable unit of 4 blue and 4 white 20-
                             Evidence level:   90  percentile     watt fluorescent lamps
                             1 -            Apgar scores ≥ 7 at 1 and 5   Irradiance at baby skin levels was 5–
                                            minutes
                                                                          2
                                                                  6microW/cm /nm
                                            Exclusion:            Babies moved every 4 hours for feeding
                                            Perinatal complication
                                            Congenital anomalies   Phototherapy discontinued at TSB
                                            Possible haemolysis   < 205 micromol/litre

                                            Demographics:
                                            Gender (M/F): 12/14
                                            Mean GA: 39.0 ± 0.8 weeks
                                            Mean BW: 3364 ± 334 gms
                                            Age at entry to study:
                                            97.2 ± 22.4 hours

                                            Mean TSB:
                                            221 ± 13 micromol/litre


              Author: Lewis H   Methodology:   n: 40              Group 1:                   ET:
                             RCT                                  Conventional Phototherapy   Group 1: 0/20
              Year: 1982                    Inclusion:                                       Group 2: 0/20
                             Blinding:      Birthweight > 2500gms,   Group 2:
              Country: UK    Not reported   Gestational Age > 37 weeks,   Conventional Phototherapy -   Treatment failure:
                                            TSB ≥ 250 micromol/litre   Delayed (initiated if TSB rose to   Group 1: 0/20
                131
              ID:            Randomisation:                       ≥ 320 micromol/litre       Group 2: 3/20
                             Random numbers   Exclusion:          :
                             table          Perinatal asphyxia,
                                            Apgar score < 5 at 4 minutes,   Conventional Phototherapy consisted of
                             Evidence level:   Positive DAT test   a Vickers 80 white light phototherapy
                             1 +                                  unit mounted 50 cm above the baby.
                                            Demographics:
                                            Gender (M/F): 27/13   Babies were blindfolded, naked except
                                            Mean GA: Not reported   for a napkin while nursing and were
                                            Mean BW: 3200 ± 260 gms   turned every 3 hours.

                                            Age at entry to study: 84 hours

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