Page 380 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
Author: Sisson T Methodology: n: 35 Group 1: ET: TSB levels – change
RCT No treatment Group 1: 2/14 Incomplete data
Year: 1971 Inclusion: TSB Group 2: 3/21
Blinding: > 162 micromol/litre Group 2: Mean change in TSB:
Country: USA Not reported Conventional phototherapy Treatment failure: Incomplete data
Exclusion: Group 1: 9/16
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ID: Randomisation: Sepsis, Conventional Phototherapy consisted of Group 2: 2/19 Time to max TSB (hours):
Coin toss Cephalhaematoma 10 (20 watt) fluorescent lamps Incomplete data
Massive ecchymosis Units were 45 cm above the baby and
Evidence level: had a Plexiglas shields to block
1 - Demographics: ultraviolet radiation.
Gender (M/F) :16/19 Canopies were vented so lamp heat was
Mean GA: Not reported dissipated
Mean BW: 2567 ± 709 gms
Age at entry to study: Not Babies removed for no more than 20
reported minutes a time for feeding etc

Babies were naked except for eye
Mean TSB: 193 micromol/litre shields and diapers

Light band = 410 – 490

Phototherapy discontinued at TSB
< 145 micromol/litre

Author: Meloni T Methodology: n: 24 Group 1:No treatment ET:
RCT Group 1: 6/12
Year: 1974 Inclusion: TSB Group 2: Group 2: 2/12
Blinding: > 188 micromol/litre Conventional phototherapy
Country: Italy Not reported
Exclusion: Conventional Phototherapy consisted of Treatment failure:
ID: Randomisation: Unclear continuous phototherapy for 96 - Group 1: 6/12
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Not reported 120 hours Group 2: 2/12
Demographics: 8 cool white fluorescent tubes which
Evidence level: Gender (M/F): Not reported deliver (at mattress level) 13.5 ± 3.5
1 - Mean GA: Not reported 2
Mean BW: Not reported watts/m
Age at entry to study: Not
reported

Mean TSB:
209 ± 24 micromol/litre

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