Page 377 - 16Neonatal Jaundice_compressed

Appendix H: Evidence tables

Phototherapy

Bibliographic Study Type & Number of Intervention & Comparison Dichotomous outcomes Continuous Outcomes
Information Evidence Level Patients/Characteristics (E:C) (Mean:SD: N)
Author: NICHHD Methodology: n: 1339 Group 1: ET:
RCT Usual care BW less than 2000 g
Year:1985 Inclusion: Group 1: 22/462
Blinding: BW < 2000gms Group 2: Group 2: 110/460
Country: USA Not reported or Conventional phototherapy
BW between 2000 gms and BW between 2000 gms
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ID: Randomisation: 2500 gms and TSB Conventional Phototherapy (Air and 2500 gms
Random numbers > 171 micromol/litre in 96 hours Shields) consisted of 96 hours (with 30 Group 1: 3/70
table, or min breaks every 4 hours for feeding Group 2: 18/71
Sealed envelopes BW > 2500 and TSB etc)
> 222 micromol/litre in 96 hours Daylight fluorescent bulbs 35 – 55cm BW above 2500 gms
Evidence level: above the baby. Group 1: 14/140
1 ++ Exclusion: Group 2: 23/136
Rh hemolysis Baby naked and with eye pads (changed
TSB > 171 micromol/litre in every 8 hours)
24 hours :
Babies with severe Irradiance measured with a light
conditions/anomalies who care monitoring badge
would be compromised by
protocol Babies received 25ml/kg of body weight
extra fluids
Demographics:
BW less than 2000 gms
Gender (M/F) :Not reported
Mean GA: Not reported
Mean BW: Not reported
Mean age at entry to study:
24.2 ± 8.0 hours
Mean TSB:
97 ± 33 micromol/litre

BW between 2000 gms and
2500 gms
Gender (M/F): 73/66
Mean GA: Not reported
Mean BW: Not reported
Age at entry to study:
62.6 ± 17.1 hours

Mean TSB:
212 ± 37 micromol/litre

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