Page 394 - 16Neonatal Jaundice_compressed
P. 394

Neonatal jaundice


              Bibliographic   Study Type &   Number of            Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
              Information    Evidence Level   Patients/Characteristics                       (E:C)             (Mean:SD: N)
                157
              ID:            not reported but   Malformations,    – Therapie 800) consisted of a standard
                             shuffled, sealed   Perinatal asphyxia,   unit of blue lamp with two filters
                             envelopes used   Respiratory distress, renal or   (infrared and uiltraviolet)
                                            gastrointestinal abnormalities,   .
                             Evidence level:   Patent ductus arteriosus,   Babies were naked except for eye
                             1 +            hypotension,          patches.
                                            Hypertension,
                                            Infection,            Fiberoptic phototherapy (BiliBlanket)
                                            Anaemia,
                                            polycythemia

                                            Demographics:
                                            Gender (M/F): 21/18
                                            Mean GA: 34.3 weeks
                                            Mean BW: 2101 g
                                            Age at entry to study
                                            Not reported
                                            Mean TSB: Not reported
              Author:        Methodology:   N: 26                 Group 1:                   ET:               Mean duration of phototherapy
              Holtrop P      RCT                                  Conventional phototherapy   Group 1: 0/14    Group 1: Not reported
                                            Inclusion:                                       Group 2: 0/12     Group 2: Not reported
              Year:          Blinding:      Birthweight > 2500 gms,   Group 2:
              1992           Not reported   Age > 1 day,          Fiberoptic phototherapy    Treatment failure:   :
                                            No Rh incompatibility,                           Group 1: 1/14
              Country:       Randomisation:   Clinical need for phototherapy   Conventional phototherapy (Olympic   Group 2: 3/12
              USA            Computer generated                   Bili-lite) consisted of an overhead bank
                                            Exclusion:            of 4 white and 4 blue 35 cm above the
                141
              ID:            Evidence level:   Not reported       baby. Babies were naked except for
                             1 +                                  diapers and eye patches. Babies were
                                            Demographics:         removed for feeding.
                                            Gender (M/F): 17/9    Mean irradiance was
                                                                                2
                                            Mean GA: 38.1 ± 2.5 weeks   9.2 ± 0.9microW/cm /nm
                                            Mean BW: 3377 ± 541 gms
                                            Age at entry to study     Fiberoptic phototherapy (Wallaby
                                            66.3 ± 19.4 hours     Phototherapy System) consisted of a
                                            Mean TSB:             cummerbund which was wrapped
                                            231 ± 24 micromol/litre   around the torso. Babies wore eye
                                                                  patches.
                                                                  Mean irradiance was
                                                                                2
                                                                  8.2 ± 1.2microW/cm /nm


                                                                  Babies were removed form the study if
                                                                  the TSB rose by more than
                                                                  9 micromol/litre/h
              Author: Pezzati M   Methodology:   N: 41            Group 1:                   ET:               Mean duration of phototherapy


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