Page 395 - 16Neonatal Jaundice_compressed
P. 395

Neonatal jaundice


 Bibliographic   Study Type &   Number of   Intervention & Comparison   Dichotomous outcomes   Continuous Outcomes
 Information   Evidence Level   Patients/Characteristics   (E:C)   (Mean:SD: N)
 157
 ID:     not reported but   Malformations,   – Therapie 800) consisted of a standard
 shuffled, sealed   Perinatal asphyxia,   unit of blue lamp with two filters
 envelopes used   Respiratory distress, renal or   (infrared and uiltraviolet)
    gastrointestinal abnormalities,   .
 Evidence level:   Patent ductus arteriosus,   Babies were naked except for eye
 1 +   hypotension,   patches.
     Hypertension,
 Infection,   Fiberoptic phototherapy (BiliBlanket)
 Anaemia,
 polycythemia

 Demographics:
 Gender (M/F): 21/18
 Mean GA: 34.3 weeks
 Mean BW: 2101 g
 Age at entry to study
 Not reported
 Mean TSB: Not reported
 Author:   Methodology:   N: 26   Group 1:   ET:   Mean duration of phototherapy
 Holtrop P   RCT      Conventional phototherapy   Group 1: 0/14   Group 1: Not reported
       Inclusion:      Group 2: 0/12   Group 2: Not reported
 Year:   Blinding:   Birthweight > 2500 gms,   Group 2:
 1992   Not reported   Age > 1 day,   Fiberoptic phototherapy   Treatment failure:   :
       No Rh incompatibility,      Group 1: 1/14
 Country:   Randomisation:   Clinical need for phototherapy   Conventional phototherapy (Olympic   Group 2: 3/12
 USA   Computer generated      Bili-lite) consisted of an overhead bank
       Exclusion:   of 4 white and 4 blue 35 cm above the
 141
 ID:     Evidence level:   Not reported   baby. Babies were naked except for
 1 +      diapers and eye patches. Babies were
     Demographics:   removed for feeding.
 Gender (M/F): 17/9   Mean irradiance was
 2
 Mean GA: 38.1 ± 2.5 weeks   9.2 ± 0.9microW/cm /nm
 Mean BW: 3377 ± 541 gms
 Age at entry to study     Fiberoptic phototherapy (Wallaby
 66.3 ± 19.4 hours   Phototherapy System) consisted of a
 Mean TSB:   cummerbund which was wrapped
 231 ± 24 micromol/litre   around the torso. Babies wore eye
 patches.
 Mean irradiance was
 2
 8.2 ± 1.2microW/cm /nm


 Babies were removed form the study if
 the TSB rose by more than
 9 micromol/litre/h
 Author: Pezzati M   Methodology:   N: 41   Group 1:   ET:   Mean duration of phototherapy


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