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The survival rate of regenerated plantlets was after the same durations. When varying number
85-90%. (10, 20, 30, 40 and 50) of prey (larvae or adults)
were provided to a single predator it fed 5.0, 6.6,
420 HOSSAIN, M.A.; SALEHUDDIN, S.M. 6.8, 9.0 and 9.4 larvae against 3.2, 3.2,3.4,3.6 and
(Chemistry Division, Atomic Energy Centre, 3.6 adults respectively.
Dhaka) & ISMAIL, Z. (School of Pharmaceutical
Sciences, University Sains Malaysia, Malaysia). 422 MAHABUB-UZ-ZAMAN, M.; MAHMUD,
Rosmarinic Acid and Methyl Rosmarinate from J. I.; AHMED, N.U.; AKTER, R.; AHMED, K.;
Orthosiphon Stamineus Benth. J. Bang. Acad. Sci., BHATTACHARGEE, S.C. & AHMED, J.
2006, 30(2), 167-171. (BCSIR Laboratories, Chittagong). Anti-inflammatory,
analgesic and antipyretic activities of ethanol leaf
Rosmarinic acid and methyl rosmarinate have been extract of Chromolaena odorata (L.) R. M. King &
isolated from Orthosiphon stamineus, Benth, a H. Robinson. Bang. J. Life Sci., 2008, 20 (2), 87-
tropical herb in Malaysia. Structural elucidation 93.
1
13
and assignment of H-NMR, C-NMR, IR UV and
mass spectroscopic data to methyl rosmarinate are The present study was carried out to investigate the
included. Anti-inflammatory, analgesic and antipyretic
activities of the ethanol leaf extract of
421 KHALEQUZZAMAN, M.; MONDAL, M.; Chromolaena odorata on experimental animal
HAQUE, M.F. & KARIM, M.S. (Dept. of model at the dose of 1g/kg body weight. Two well
Zoology, Rajshahi University, Rajshahi). Predatory established model carrageenan induced paw edema
Efficacy of Phytoseiulus Persimilis Athias-Henriot and cotton pellet induced granuloma formation
(Acari: Phytoseiidae) on the two Spotted Spider were used for evaluating anti-inflammatory
Mite Tetranychus Urticae Koch (Acari: property. Analgesic activity was assessed in mice
Tetranychidae). J. Bio-Sci., 2007, 15, 127-132. using acetic acid induced writhing response.
The relative abundance Tetranychus urticae and Antipyretic activily was also investigated on yeast-
Phytoseiulus persimilis as well as voracity of the induced pyrexia in rats. Acute toxicity test was
predator were conducted on potted eggplants. After performed in rats after administration of the extract
six weeks of release of ten female T. urticae in orally at high dose level (4g/kg). Oral
control plants, the highest mite population reached administralion of the ethanol extract of
at 184.21/ leaf, against 67.92 and 107.48/ leaf in Chromolaena odorata significantly (P<0.01)
st
plants which received two predators after 1 and suppressed the paw edema induced by carrageenan
rd
3 week respectively. After nine weeks the number as well as granulomatous tissue formation induced
of mite / leaf reduced to 13.21 and 23.97 / leaf by cotton pellet in rats successfully. In addition, an
rd
st
after 1 and 3 week of introduction of the appreciable antipyretic effect was also noticed with
predator, the control population was 81.32. Adult ethanol extract but no significant analgesic activity
P. persimilis as single predator fed 8.2, 15.4 and was observed. In acute loxicity study, no mortality
20.6 T. urticae eggs after 24, 48 and 72 h was observed at 4 g/kg dose level. The present
respectively. Again a single predator when tested study demonstrates the potential anti-inflammatory
separately fed 5.4, 10.8 and 14.6 T. urticae larvae and antipyretic effect of the ethanol leaf extract of
after 24, 48 and 72 h respectively. A single adult Chromolaena odorata, which supports the claims
predator fed on 3.6, 7.0 and 12.0 adult T. urticae by the traditional medicine practioners.
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