Page 401 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C3.1 Studies on offer, acceptance, and adherence of active surveillance (continued)
Factors examined Author Study approach AS/WW definitions Findings Issues
Year
PMID
Patient and Diefenbach 185 Survey of 654 men (77% RT; 17% WW (not explicitly • Most influential in reaching a • Unclear if WW was
physician 2002 RP; 6% WW) with early stage provided) treatment decision: physician actively offered by
factors affecting 11828358 disease recruited by either a recommendation (51%), advice urologists or radiation
acceptance urologist or radiation oncologist; pts from family and friends (19%), oncologists to patients
presented to Fox Chase Cancer information from books and since only 6% opted for
Center or an affiliated hospital for journals (18%), Internet (7%), WW
an opinion regarding treatment disease and treatment factors
options; eligibility criteria included (3%)
early-stage disease; not yet • Patients who chose RP over
decided on a treatment; free of RT or WW perceived prostate
substantial comorbidity, and ability cancer as a significantly more
to communicate in English serious disease (P <0.001)
What MD would Durham 184 Survey (of screening behaviors, WW: not defined (non- • For men with localized • Survey of GPs given
offer based on 2003 with case vignettes, piloted for curative) prostate cancer, GPs responded theoretical cases
expected life 12835804 understandability and face validity that (vignettes)
expectancy on 10 GPs) of GPs (in New If life expectancy <10 y, WW • No data urban vs. rural
Zealand), equalized urban vs. rural. would be suggested treatment • Survey response rate
201 urban, 180 rural GPs (45%), followed by hormone 66%
responded. Survey sent to a (23%), RT (13%), prostatectomy
random national sample of 575 (8%), other combinations (6%)
New Zealand GPs, stratified to
include equal number of rural and • If life expectancy >10 y, WW
urban GPs; 66.3% responded suggested 3%; prostatectomy
53%, other combination 17%,
RT 14%, hormone 8%

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