Page 396 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
P. 396

Appendix Table C3.1 Studies on offer, acceptance, and adherence of active surveillance

                                           Factors         Author                     Study approach                       AS/WW                          Findings                              Issues
                                          examined           Year                                                        definitions
                                                            PMID
                                        Physicians       Crawford  193   Random phone survey of 1000 men from           WW (not          •   83% patients and 76% urologists            •   200/335 urologists
                                        factors          1997           the 30,000 men in the prostate cancer           explicitly       preferred aggressive therapy                   and 780/1000
                                        affecting offer   9301699       support group (US TOO), of which 780 men        provided)        •  Treatment options for men with              patients responded to
                                                                        responded; and survey of 200 urologists                          localized disease and few comorbidities,       the survey
                                                                        (details of sampling population of urologists                    urologists on the average would prefer RP      •   Urologists in this
                                                                        not provided)                                                    (67%), RT (29%), WW (4%)                       survey were not
                                                                                                                                         •  Different perspectives on whether           necessarily the
                                                                                                                                         treatment options were discussed: 20%          urologists who took
                                                                                                                                         patients felt treatment options were not       care of the patients in
                                                                                                                                         discussed while 1% urologists felt             the survey
                                                                                                                                         treatment options were not discussed
                                        Patient          Berry 191      Content analysis of 13 men in focus groups      WW (not          •   20/44 men who relied on influential        •  Small sample size
                                        factors          2003           and 31 men in individual unstructured           explicitly       others (an individual whose illness
                                        affecting        12856636       interviews; men were within 6 mo dx of          provided)        experience and/or story had explicit
                                        acceptance                      localized prostate cancer; sample of 44                          influence on the participant’s treatment
                                                                        obtained from 68 eligible men from 3                             decision) to make a treatment decision, 1
                                                                        urology clinics and flyer and newspaper                          broadened the horizon to consider WW, 1
                                                                        announcements                                                    moved away from considering WW
                                        Patient          Chapple  189    Interview 50 men from UK with all stages of    WW = no          •   Few men who chose WW had                   •   Men with all
                                        factors          2002           prostate cancer, 4 of whom chose WW;            active           consulted the Internet, concerned about        stages of disease in
                                        affecting        12133062       sample chosen to include men at different       treatment        the side-effects and uncertain treatment       UK
                                        acceptance                      stages of dx; recruited through GPs,                             outcomes, and found physicians who were        •   Small sample size
                                                                        urologists, support groups and charities;                        supportive of their decision
                                                                        although great effort to recruit minorities,
                                                                        few volunteered


























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