Page 399 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C3.1 Studies on offer, acceptance, and adherence of active surveillance (continued)
Factors examined Author Study approach AS/WW definitions Findings Issues
Year
PMID
Patient factors Davison 183 Qualitative description of interviews Implied; details not • MD description of prostate ca • Small sample size
affecting 2009 of 25 of 45 eligible men with low provided (patients from affects patient perception of the • Limited applicability
acceptance 19136342 risk prostate ca on AS; sample of 2 large tertiary care seriousness of the condition and
English speaking men with low-risk centers that support affects treatment choice
prostate cancer currently on AS AS) • MD recommendation most
recruited from the Prostate Centre influential on patient decision to
at Vancouver General Hospital and select AS
the British Columbia Cancer • Concerns about impotency
Agency (large urban tertiary referral and incontinence affects
centers for the province of British treatment choice
Columbia)
Patient factors Demark- Survey of 231 men (50% Black) WW (not explicitly • WW discussed ≥ high • No statistical
affecting offer Wahnefried 190 with prostate cancer in N. Carolina; provided) school vs. <high school adjustment
1998 stratified design to recruit 240 men education 59.5% v. 43.7%
9669815 evenly sampled with respect to race (P<0.05)
(50% black; 50% white) and stage • MD recommendation most
(local, regional and distant disease) influential in treatment decision
within the N. Carolina Central (57%) (no differences between
Cancer Registry; eligibility included Blacks and Whites (no
ages 50-74 y; dx’d between 1994- numerical data); urban vs. rural
95; reside in a region comprising 63 (62.3% vs. 43.9%, P=0.004))
contiguous counties where >20% • Differences NS in WW
were black; dx’d at 1 of 16 hospitals options discussed between rural
or clinics with IRB approval; cancer and urban residents (53.7% vs.
registry included phone contact 51.9%)
• Differences NS in WW
options discussed between
Blacks and Whites (48.7% vs.
56.1%)

C-117