Page 398 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C3.1 Studies on offer, acceptance, and adherence of active surveillance (continued)
Factors examined Author Study approach
Year
PMID
Patient factors Davison 183 Qualitative description of interviews
affecting 2009 of 25 of 45 eligible men with low
acceptance 19136342 risk prostate ca on AS; sample of
English speaking men with low-risk
prostate cancer currently on AS
recruited from the Prostate Centre
at Vancouver General Hospital and
the British Columbia Cancer
Agency (large urban tertiary referral
centers for the province of British
Columbia)
Patient factors Demark- Survey of 231 men (50% Black)
affecting offer Wahnefried 190 with prostate cancer in N. Carolina;
1998 stratified design to recruit 240 men
9669815 evenly sampled with respect to race
(50% black; 50% white) and stage
(local, regional and distant disease)
within the N. Carolina Central
Cancer Registry; eligibility included
ages 50-74 y; dx’d between 1994-
95; reside in a region comprising 63
contiguous counties where >20%
were black; dx’d at 1 of 16 hospitals
or clinics with IRB approval; cancer
registry included phone contact
AS/WW definitions Findings Issues
Implied; details not • MD description of prostate ca • Small sample size
provided (patients from affects patient perception of the • Limited applicability
2 large tertiary care seriousness of the condition and
centers that support affects treatment choice
AS) • MD recommendation most
influential on patient decision to
select AS
• Concerns about impotency
and incontinence affects
treatment choice
WW (not explicitly • WW discussed ≥ high • No statistical
provided) school vs. <high school adjustment
education 59.5% v. 43.7%
(P<0.05)
• MD recommendation most
influential in treatment decision
(57%) (no differences between
Blacks and Whites (no
numerical data); urban vs. rural
(62.3% vs. 43.9%, P=0.004))
• Differences NS in WW
options discussed between rural
and urban residents (53.7% vs.
51.9%)
• Differences NS in WW
options discussed between
Blacks and Whites (48.7% vs.
56.1%)
C-117